Cargando…

Hypoxic Non-Small-Cell Lung Cancer Cell-Secreted Exosomal microRNA-582-3p Drives Cancer Cell Malignant Phenotypes by Targeting Secreted Frizzled-Related Protein 1

BACKGROUND: Hypoxic environment and exosomes (exos)-mediated intercellular communication are crucial for cancer invasion and metastasis, but the mechanisms are not yet fully understood. In this study, we investigated the regulatory effect of hypoxic tumor cell-secreted exosomal miR-582-3p on non-sma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Jian, Zhao, Jia, Zhu, Jinsong, Zhang, Shengli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569064/ https://www.ncbi.nlm.nih.gov/pubmed/33116870 http://dx.doi.org/10.2147/CMAR.S263768

Ejemplares similares

Exosome secretion from hypoxic cancer cells reshapes the tumor microenvironment and mediates drug resistance
por: To, Kenneth K. W., et al.
Publicado: (2022)

Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma
por: Jayabal, Panneerselvam, et al.
Publicado: (2023)

Frizzled-Dependent Planar Cell Polarity without Secreted Wnt Ligands
por: Yu, Joyce J.S., et al.
Publicado: (2020)

Cardiac hormones are potent inhibitors of secreted frizzled-related protein-3 in human cancer cells
por: SKELTON, WILLIAM P., et al.
Publicado: (2013)

TTK (threonine tyrosine kinase) regulates the malignant behaviors of cancer cells and is regulated by microRNA-582-5p in ovarian cancer
por: Lu, Na, et al.
Publicado: (2021)

Exosomes Secreted by Normoxic and Hypoxic Cardiosphere-derived Cells Have Anti-apoptotic Effect
por: Namazi, Helia, et al.
Publicado: (2018)

Promoting roles of the secreted frizzled-related protein 2 as a Wnt agonist in lung cancer cells
por: XIAO, XIAOMIN, et al.
Publicado: (2015)

Effects of secreted frizzled-related protein 1 on proliferation, migration, invasion, and apoptosis of colorectal cancer cells
por: Wang, Zhongchuan, et al.
Publicado: (2018)

Regulation of Cancer Stem Cell Metabolism by Secreted Frizzled-Related Protein 4 (sFRP4)
por: Deshmukh, Abhijeet, et al.
Publicado: (2018)

Rab35 drives exosome secretion
por: Short, Ben
Publicado: (2010)

The Primary Cilium as a Biomarker in the Hypoxic Adaptation of Bone Marrow-Derived Mesenchymal Stromal Cells: A Role for the Secreted Frizzled-Related Proteins
por: Proulx-Bonneau, Sébastien, et al.
Publicado: (2011)

Secreted Frizzled Related Proteins in Cardiovascular and Metabolic Diseases
por: Guan, Hua, et al.
Publicado: (2021)

Exosomes secreted from human colon cancer cells influence the adhesion of neighboring metastatic cells: Role of microRNA-210
por: Bigagli, Elisabetta, et al.
Publicado: (2016)

Loss of Secreted Frizzled-Related Protein 4 Correlates with an Aggressive Phenotype and Predicts Poor Outcome in Ovarian Cancer Patients
por: Jacob, Francis, et al.
Publicado: (2012)

Methylation and Loss of Secreted Frizzled-Related Protein 3 Enhances Melanoma Cell Migration and Invasion
por: Ekström, Elin J., et al.
Publicado: (2011)

Hepatocellular Carcinoma Cell-Secreted Exosomal MicroRNA-210 Promotes Angiogenesis In Vitro and In Vivo
por: Lin, Xue-Jia, et al.
Publicado: (2018)

Non–small cell lung cancer-derived exosomes promote proliferation, phagocytosis, and secretion of microglia via exosomal microRNA in the metastatic microenvironment
por: Chen, Peng, et al.
Publicado: (2022)

Exosomes secreted by chemoresistant ovarian cancer cells promote angiogenesis
por: Li, Zhang, et al.
Publicado: (2021)

Secreted Frizzled-Related Protein 2 Is Associated with Disease Progression and Poor Prognosis in Breast Cancer
por: Huang, Chumei, et al.
Publicado: (2019)

Role of Secreted Frizzled-Related Protein 1 in Early Breast Carcinogenesis and Breast Cancer Aggressiveness
por: Clemenceau, Alisson, et al.
Publicado: (2023)

Colon cancer cells secrete exosomes to promote self-proliferation by shortening mitosis duration and activation of STAT3 in a hypoxic environment
por: Ren, Ruixue, et al.
Publicado: (2019)

Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles
por: Guo, Haiying, et al.
Publicado: (2019)

Secreted frizzled-related protein 4 promotes brown adipocyte differentiation
por: Guan, Hua, et al.
Publicado: (2021)

Effect of Secreted Frizzled-Related Protein 5 in Mice with Heart Failure
por: Hong, Pan, et al.
Publicado: (2022)

Secretion of Mutant DNA and mRNA by the Exosomes of Breast Cancer Cells
por: Andreeva, Olga E., et al.
Publicado: (2021)

EMT Participates in the Regulation of Exosomes Secretion and Function in Esophageal Cancer Cells
por: Chen, Chuangui, et al.
Publicado: (2021)

MicroRNA-582-5p suppresses non-small cell lung cancer cells growth and invasion via downregulating NOTCH1
por: Liu, Jianghong, et al.
Publicado: (2019)

HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8(+) T-cell infiltration into tumors
por: Guan, Lei, et al.
Publicado: (2022)

Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line
por: Ohshima, Keiichi, et al.
Publicado: (2010)

Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer
por: Kawano, Y, et al.
Publicado: (2009)

Secreted Frizzled-Related Protein Promotes Bone Regeneration by Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Katagiri, Wataru, et al.
Publicado: (2015)

Secreted Frizzled-Related Protein 1 Promotes Odontoblastic Differentiation and Reparative Dentin Formation in Dental Pulp Cells
por: Ipposhi, Keita, et al.
Publicado: (2021)

Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo
por: De Langhe, Ellen, et al.
Publicado: (2014)

The Overexpression of TOB1 Induces Autophagy in Gastric Cancer Cells by Secreting Exosomes
por: Wang, Yanhong, et al.
Publicado: (2022)

A MicroRNA Derived From Schistosoma japonicum Promotes Schistosomiasis Hepatic Fibrosis by Targeting Host Secreted Frizzled-Related Protein 1
por: Wang, Yange, et al.
Publicado: (2020)

Downregulation of senescence-associated secretory phenotype by knockdown of secreted frizzled-related protein 4 contributes to the prevention of skin aging
por: Takaya, Kento, et al.
Publicado: (2022)

Hypoxic enhancement of exosome release by breast cancer cells
por: King, Hamish W, et al.
Publicado: (2012)

Arsenic trioxide inhibits viability and induces apoptosis through reactivating the Wnt inhibitor secreted frizzled related protein-1 in prostate cancer cells
por: Zheng, Lei, et al.
Publicado: (2016)

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells
por: Yang, Mei, et al.
Publicado: (2011)

Silencing of carbonic anhydrase I enhances the malignant potential of exosomes secreted by prostatic tumour cells
por: Bánová Vulić, Radivojka, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_qrfrsomp81qjdid1qduhea1tp6