Cargando…
Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease
Patients with nodular–bronchiectatic MAC lung disease have dysregulated adaptive immunity with defective IL-17 and IFN-γ production, and IL-10 overproduction. This suggests a role for adjunctive immunomodulatory treatments. https://bit.ly/33AALwx
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Respiratory Society
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569207/ https://www.ncbi.nlm.nih.gov/pubmed/33123562 http://dx.doi.org/10.1183/23120541.00548-2020 |
| _version_ | 1783596683549999104 |
|---|---|
| author | Bruno, Mariolina Zweijpfenning, Sanne M.H. Verhoeven, Jeske Boeree, Martin J. Netea, Mihai G. van de Veerdonk, Frank L. van Ingen, Jakko Hoefsloot, Wouter |
| author_facet | Bruno, Mariolina Zweijpfenning, Sanne M.H. Verhoeven, Jeske Boeree, Martin J. Netea, Mihai G. van de Veerdonk, Frank L. van Ingen, Jakko Hoefsloot, Wouter |
| author_sort | Bruno, Mariolina |
| collection | PubMed |
| description | Patients with nodular–bronchiectatic MAC lung disease have dysregulated adaptive immunity with defective IL-17 and IFN-γ production, and IL-10 overproduction. This suggests a role for adjunctive immunomodulatory treatments. https://bit.ly/33AALwx |
| format | Online Article Text |
| id | pubmed-7569207 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | European Respiratory Society |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-75692072020-10-28 Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease Bruno, Mariolina Zweijpfenning, Sanne M.H. Verhoeven, Jeske Boeree, Martin J. Netea, Mihai G. van de Veerdonk, Frank L. van Ingen, Jakko Hoefsloot, Wouter ERJ Open Res Original Research Letters Patients with nodular–bronchiectatic MAC lung disease have dysregulated adaptive immunity with defective IL-17 and IFN-γ production, and IL-10 overproduction. This suggests a role for adjunctive immunomodulatory treatments. https://bit.ly/33AALwx European Respiratory Society 2020-10-19 /pmc/articles/PMC7569207/ /pubmed/33123562 http://dx.doi.org/10.1183/23120541.00548-2020 Text en Copyright ©ERS 2020 http://creativecommons.org/licenses/by-nc/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. |
| spellingShingle | Original Research Letters Bruno, Mariolina Zweijpfenning, Sanne M.H. Verhoeven, Jeske Boeree, Martin J. Netea, Mihai G. van de Veerdonk, Frank L. van Ingen, Jakko Hoefsloot, Wouter Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease |
| title | Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease |
| title_full | Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease |
| title_fullStr | Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease |
| title_full_unstemmed | Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease |
| title_short | Subtle immunodeficiencies in nodular–bronchiectatic Mycobacterium avium complex lung disease |
| title_sort | subtle immunodeficiencies in nodular–bronchiectatic mycobacterium avium complex lung disease |
| topic | Original Research Letters |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569207/ https://www.ncbi.nlm.nih.gov/pubmed/33123562 http://dx.doi.org/10.1183/23120541.00548-2020 |
| work_keys_str_mv | AT brunomariolina subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT zweijpfenningsannemh subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT verhoevenjeske subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT boereemartinj subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT neteamihaig subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT vandeveerdonkfrankl subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT vaningenjakko subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease AT hoefslootwouter subtleimmunodeficienciesinnodularbronchiectaticmycobacteriumaviumcomplexlungdisease |