The Role of Mast Cells in Aspirin-Exacerbated Respiratory Disease (AERD) Pathogenesis: Implications for Future Therapeutics

Mast cells (MC) have recently been demonstrated to play an integral role in the pathogenesis of aspirin-exacerbated respiratory disease (AERD). When activated, MCs release pre-formed granules of many pro-inflammatory mediators, including histamine, serotonin, and various chemokines and cytokines inc...

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Detalles Bibliográficos
Autores principales: Kuruvilla, Merin E, Vanijcharoenkarn, Kristine, Levy, Joshua M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569245/
https://www.ncbi.nlm.nih.gov/pubmed/33116654
http://dx.doi.org/10.2147/JAA.S237463

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