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Infection prevention in sarcoidosis: proposal for vaccination and prophylactic therapy

Sarcoidosis is a systemic inflammatory disease characterized by granuloma formation in affected organs and caused by dysregulated immune response to an unknown antigen. Sarcoidosis patients receiving immunosuppressive medications are at increased risk of infection. Lymphopenia is also commonly seen...

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Detalles Bibliográficos
Autores principales: Syed, Huzaefah, Ascoli, Christian, Linssen, Catharina FM, Vagts, Christen, Iden, Thomas, Syed, Aamer, Kron, Jordana, Polly, Kelly, Perkins, David, Finn, Patricia W, Novak, Richard, Drent, Marjolein, Baughman, Robert, Sweiss, Nadera J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569559/
https://www.ncbi.nlm.nih.gov/pubmed/33093774
http://dx.doi.org/10.36141/svdld.v37i2.9599
Descripción
Sumario:Sarcoidosis is a systemic inflammatory disease characterized by granuloma formation in affected organs and caused by dysregulated immune response to an unknown antigen. Sarcoidosis patients receiving immunosuppressive medications are at increased risk of infection. Lymphopenia is also commonly seen among patient with sarcoidosis. In this review, risk of infections, including opportunistic infections, will be outlined. Recommendations for vaccinations and prophylactic therapy based on literature review will also be summarized. (Sarcoidosis Vasc Diffuse Lung Dis 2020; 37 (2): 87-98).