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Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis

Antihistamines are the cornerstone treatment of allergic rhinitis (AR). To quantify the antihistaminic consume is particularly relevant in clinical practice, since a remarkable use is usually associated with severe symptoms. The aim of the study was to measure the use of antihistamines in two groups...

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Autores principales: Tosca, Maria Angela, Olcese, Roberta, Marinelli, Guido, Papale, Maria, Zicari, Anna Maria, Marseglia, Gianluigi, Ciprandi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569653/
https://www.ncbi.nlm.nih.gov/pubmed/32420973
http://dx.doi.org/10.23750/abm.v91i2.9719
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author Tosca, Maria Angela
Olcese, Roberta
Marinelli, Guido
Papale, Maria
Zicari, Anna Maria
Marseglia, Gianluigi
Ciprandi, Giorgio
author_facet Tosca, Maria Angela
Olcese, Roberta
Marinelli, Guido
Papale, Maria
Zicari, Anna Maria
Marseglia, Gianluigi
Ciprandi, Giorgio
author_sort Tosca, Maria Angela
collection PubMed
description Antihistamines are the cornerstone treatment of allergic rhinitis (AR). To quantify the antihistaminic consume is particularly relevant in clinical practice, since a remarkable use is usually associated with severe symptoms. The aim of the study was to measure the use of antihistamines in two groups of children suffering from AR. The first group took a course of a nutraceutical (Lertal®) before the observation (active group, AG); a second one was considered as control (control group, CG). Both groups took antihistamines on demand. The children were visited at baseline and after 1 year. The number of days of antihistaminic use was the primary outcome. Children in AG had a significant reduced number of antihistamines use in comparison with CG (p=0.008). In conclusion, the current study showed that a course with a multicomponent nutraceutical could reduce the use of symptomatic antihistamines in children with allergic rhinoconjunctivitis. (www.actabiomedica.it)
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spelling pubmed-75696532020-10-21 Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis Tosca, Maria Angela Olcese, Roberta Marinelli, Guido Papale, Maria Zicari, Anna Maria Marseglia, Gianluigi Ciprandi, Giorgio Acta Biomed Focus on Antihistamines are the cornerstone treatment of allergic rhinitis (AR). To quantify the antihistaminic consume is particularly relevant in clinical practice, since a remarkable use is usually associated with severe symptoms. The aim of the study was to measure the use of antihistamines in two groups of children suffering from AR. The first group took a course of a nutraceutical (Lertal®) before the observation (active group, AG); a second one was considered as control (control group, CG). Both groups took antihistamines on demand. The children were visited at baseline and after 1 year. The number of days of antihistaminic use was the primary outcome. Children in AG had a significant reduced number of antihistamines use in comparison with CG (p=0.008). In conclusion, the current study showed that a course with a multicomponent nutraceutical could reduce the use of symptomatic antihistamines in children with allergic rhinoconjunctivitis. (www.actabiomedica.it) Mattioli 1885 2020 2020-05-11 /pmc/articles/PMC7569653/ /pubmed/32420973 http://dx.doi.org/10.23750/abm.v91i2.9719 Text en Copyright: © 2020 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Focus on
Tosca, Maria Angela
Olcese, Roberta
Marinelli, Guido
Papale, Maria
Zicari, Anna Maria
Marseglia, Gianluigi
Ciprandi, Giorgio
Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
title Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
title_full Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
title_fullStr Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
title_full_unstemmed Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
title_short Lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
title_sort lertal®, a multicomponent nutraceutical, could reduce the use of antihistamines in children with allergic rhinoconjunctivitis
topic Focus on
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569653/
https://www.ncbi.nlm.nih.gov/pubmed/32420973
http://dx.doi.org/10.23750/abm.v91i2.9719
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