Cargando…

A Genome-Scale Insight into the Effect of Shear Stress During the Fed-Batch Production of Clavulanic Acid by Streptomyces Clavuligerus

Streptomyces clavuligerus is a filamentous Gram-positive bacterial producer of the β-lactamase inhibitor clavulanic acid. Antibiotics biosynthesis in the Streptomyces genus is usually triggered by nutritional and environmental perturbations. In this work, a new genome scale metabolic network of Stre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gómez-Ríos, David, López-Agudelo, Victor A., Ramírez-Malule, Howard, Neubauer, Peter, Junne, Stefan, Ochoa, Silvia, Ríos-Estepa, Rigoberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569809/ https://www.ncbi.nlm.nih.gov/pubmed/32824882 http://dx.doi.org/10.3390/microorganisms8091255

Ejemplares similares

Characterization of the Metabolic Response of Streptomyces clavuligerus to Shear Stress in Stirred Tanks and Single-Use 2D Rocking Motion Bioreactors for Clavulanic Acid Production
por: Gómez-Ríos, David, et al.
Publicado: (2019)

TCA Cycle and Its Relationship with Clavulanic Acid Production: A Further Interpretation by Using a Reduced Genome-Scale Metabolic Model of Streptomyces clavuligerus
por: Ramirez-Malule, Howard, et al.
Publicado: (2021)

Clavulanic Acid Production by Streptomyces clavuligerus: Insights from Systems Biology, Strain Engineering, and Downstream Processing
por: López-Agudelo, Víctor A., et al.
Publicado: (2021)

Data of clavulanic acid and clavulanate-imidazole stability at low temperatures
por: Gómez-Ríos, David, et al.
Publicado: (2019)

Degradation Kinetics of Clavulanic Acid in Fermentation Broths at Low Temperatures
por: Gómez-Ríos, David, et al.
Publicado: (2019)

Environmental Factors Modulate the Role of orf21 Sigma Factor in Clavulanic Acid Production in Streptomyces Clavuligerus ATCC27064
por: Patiño, Luisa F., et al.
Publicado: (2022)

Data set of in silico simulation for the production of clavulanic acid and cephamycin C by Streptomyces clavuligerus using a genome scale metabolic model
por: Gómez-Cerón, Stephania, et al.
Publicado: (2019)

Overproduction of Clavulanic Acid by UV Mutagenesis of Streptomyces clavuligerus
por: Korbekandi, Hassan, et al.
Publicado: (2010)

Comparative Transcriptome Analysis of Streptomyces Clavuligerus in Response to Favorable and Restrictive Nutritional Conditions
por: Pinilla, Laura, et al.
Publicado: (2019)

Screening of medium constituents for clavulanic acid production by Streptomyces clavuligerus
por: Rodrigues, Kaio César da Silva, et al.
Publicado: (2018)

Comparative Analysis of Strategies for De Novo Transcriptome Assembly in Prokaryotes: Streptomyces clavuligerus as a Case Study
por: Caicedo-Montoya, Carlos, et al.
Publicado: (2019)

Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus
por: Ünsaldı, Eser, et al.
Publicado: (2016)

Transcriptome profiles of Streptomyces clavuligerus strains producing different titers of clavulanic acid
por: Gong, Junpyo, et al.
Publicado: (2023)

Metabolic adaptation of two in silico mutants of Mycobacterium tuberculosis during infection
por: López-Agudelo, Víctor A., et al.
Publicado: (2017)

Fermentation Conditions that Affect Clavulanic Acid Production in Streptomyces clavuligerus: A Systematic Review
por: Ser, Hooi-Leng, et al.
Publicado: (2016)

Genome‐wide gene expression changes in an industrial clavulanic acid overproduction strain of Streptomyces clavuligerus
por: Medema, Marnix H., et al.
Publicado: (2011)

Complete Genome Sequence of Streptomyces clavuligerus F613-1, an Industrial Producer of Clavulanic Acid
por: Cao, Guangxiang, et al.
Publicado: (2016)

Bibliometric Analysis of Global Research on Clavulanic Acid
por: Ramirez-Malule, Howard
Publicado: (2018)

Molecular Analysis of the Clavulanic Acid Regulatory Gene Isolated from an Iranian Strain of Streptomyces Clavuligerus , PTCC 1709
por: Hojati, Zohreh, et al.
Publicado: (2011)

Clavulanic acid production by the MMS 150 mutant obtained from wild type Streptomyces clavuligerus ATCC 27064
por: da Silva Vasconcelos, Eliton, et al.
Publicado: (2014)

Streptomyces clavuligerus: The Omics Era
por: Liras, Paloma, et al.
Publicado: (2021)

Enhanced production of clavulanic acid by improving glycerol utilization using reporter-guided mutagenesis of an industrial Streptomyces clavuligerus strain
por: Shin, Chang-Hun, et al.
Publicado: (2021)

In vivo functional analysis of a class A β-lactamase-related protein essential for clavulanic acid biosynthesis in Streptomyces clavuligerus
por: Srivastava, Santosh K., et al.
Publicado: (2019)

Rich Organic Nitrogen Impacts Clavulanic Acid Biosynthesis through the Arginine Metabolic Pathway in Streptomyces clavuligerus F613-1
por: Fu, Jiafang, et al.
Publicado: (2022)

The CagRS Two-Component System Regulates Clavulanic Acid Metabolism via Multiple Pathways in Streptomyces clavuligerus F613-1
por: Fu, Jiafang, et al.
Publicado: (2019)

Simultaneous solid–liquid separation and primary purification of clavulanic acid from fermentation broth of Streptomyces clavuligerus using salting‐out extraction system
por: Wang, Xu‐Dong, et al.
Publicado: (2021)

Transcriptomic analysis of Streptomyces clavuligerus ΔccaR::tsr: effects of the cephamycin C-clavulanic acid cluster regulator CcaR on global regulation*
por: Álvarez-Álvarez, R, et al.
Publicado: (2014)

Teleocidin-producing genotype of Streptomyces clavuligerus ATCC 27064
por: Pivk Lukančič, Petra, et al.
Publicado: (2022)

Exploiting Adaptive Laboratory Evolution of Streptomyces clavuligerus for Antibiotic Discovery and Overproduction
por: Charusanti, Pep, et al.
Publicado: (2012)

Specialized Metabolites from Ribosome Engineered Strains of Streptomyces clavuligerus
por: Shaikh, Arshad Ali, et al.
Publicado: (2021)

Pan-Genome of the Genus Streptomyces and Prioritization of Biosynthetic Gene Clusters With Potential to Produce Antibiotic Compounds
por: Caicedo-Montoya, Carlos, et al.
Publicado: (2021)

The effect of uncontrolled travelers and social distancing on the spread of novel coronavirus disease (COVID-19) in Colombia
por: Gómez-Ríos, David, et al.
Publicado: (2020)

Activation of Secondary Metabolite Gene Clusters in Streptomyces clavuligerus by the PimM Regulator of Streptomyces natalensis
por: Martínez-Burgo, Yolanda, et al.
Publicado: (2019)

A detailed view on 1,8-cineol biosynthesis by Streptomyces clavuligerus
por: Rinkel, Jan, et al.
Publicado: (2016)

Genome editing reveals that pSCL4 is required for chromosome linearity in Streptomyces clavuligerus
por: Gomez-Escribano, Juan Pablo, et al.
Publicado: (2021)

Elucidating the Regulatory Elements for Transcription Termination and Posttranscriptional Processing in the Streptomyces clavuligerus Genome
por: Hwang, Soonkyu, et al.
Publicado: (2021)

Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus
por: Leite, Carla A, et al.
Publicado: (2013)

Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus
por: Álvarez-Álvarez, Rubén, et al.
Publicado: (2015)

Efficient production of secretory Streptomyces clavuligerus β-lactamase inhibitory protein (BLIP) in Pichia pastoris
por: Law, Kin-Ho, et al.
Publicado: (2018)

Molecular mechanism of GylR-mediated regulation of glycerol metabolism in Streptomyces clavuligerus NRRL 3585
por: Zhang, Chaobo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_unfipqkh229h9esknc8u06u756