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Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569815/ https://www.ncbi.nlm.nih.gov/pubmed/32878290 http://dx.doi.org/10.3390/metabo10090356 |
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author | Balgoma, David Gil-de-Gómez, Luis Montero, Olimpio |
author_facet | Balgoma, David Gil-de-Gómez, Luis Montero, Olimpio |
author_sort | Balgoma, David |
collection | PubMed |
description | The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid metabolism, and the role played by diverse lipids in regard to the infection effectiveness. All these aspects have currently been tackled separately as independent issues and focused on the function of proteins. Here, we review the role of cholesterol and other lipids in ssRNA+ infection. |
format | Online Article Text |
id | pubmed-7569815 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75698152020-10-27 Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update Balgoma, David Gil-de-Gómez, Luis Montero, Olimpio Metabolites Review The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid metabolism, and the role played by diverse lipids in regard to the infection effectiveness. All these aspects have currently been tackled separately as independent issues and focused on the function of proteins. Here, we review the role of cholesterol and other lipids in ssRNA+ infection. MDPI 2020-08-31 /pmc/articles/PMC7569815/ /pubmed/32878290 http://dx.doi.org/10.3390/metabo10090356 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Balgoma, David Gil-de-Gómez, Luis Montero, Olimpio Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update |
title | Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update |
title_full | Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update |
title_fullStr | Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update |
title_full_unstemmed | Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update |
title_short | Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update |
title_sort | lipidomics issues on human positive ssrna virus infection: an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569815/ https://www.ncbi.nlm.nih.gov/pubmed/32878290 http://dx.doi.org/10.3390/metabo10090356 |
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