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Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update

The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid...

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Detalles Bibliográficos
Autores principales: Balgoma, David, Gil-de-Gómez, Luis, Montero, Olimpio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569815/
https://www.ncbi.nlm.nih.gov/pubmed/32878290
http://dx.doi.org/10.3390/metabo10090356
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author Balgoma, David
Gil-de-Gómez, Luis
Montero, Olimpio
author_facet Balgoma, David
Gil-de-Gómez, Luis
Montero, Olimpio
author_sort Balgoma, David
collection PubMed
description The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid metabolism, and the role played by diverse lipids in regard to the infection effectiveness. All these aspects have currently been tackled separately as independent issues and focused on the function of proteins. Here, we review the role of cholesterol and other lipids in ssRNA+ infection.
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spelling pubmed-75698152020-10-27 Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update Balgoma, David Gil-de-Gómez, Luis Montero, Olimpio Metabolites Review The pathogenic mechanisms underlying the Biology and Biochemistry of viral infections are known to depend on the lipid metabolism of infected cells. From a lipidomics viewpoint, there are a variety of mechanisms involving virus infection that encompass virus entry, the disturbance of host cell lipid metabolism, and the role played by diverse lipids in regard to the infection effectiveness. All these aspects have currently been tackled separately as independent issues and focused on the function of proteins. Here, we review the role of cholesterol and other lipids in ssRNA+ infection. MDPI 2020-08-31 /pmc/articles/PMC7569815/ /pubmed/32878290 http://dx.doi.org/10.3390/metabo10090356 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Balgoma, David
Gil-de-Gómez, Luis
Montero, Olimpio
Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
title Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
title_full Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
title_fullStr Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
title_full_unstemmed Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
title_short Lipidomics Issues on Human Positive ssRNA Virus Infection: An Update
title_sort lipidomics issues on human positive ssrna virus infection: an update
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569815/
https://www.ncbi.nlm.nih.gov/pubmed/32878290
http://dx.doi.org/10.3390/metabo10090356
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