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Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change

Environmental factors can influence the composition of gut microbiota, but understanding the combined effect of lifestyle factors on adult gut microbiota is limited. Here, we investigated whether changes in the modifiable lifestyle factors, such as cigarette smoking, alcohol consumption, sleep durat...

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Autores principales: Jung, YeonGyun, Tagele, Setu Bazie, Son, HyunWoo, Ibal, Jerald Conrad, Kerfahi, Dorsaf, Yun, Hyunju, Lee, Bora, Park, Clara Yongjoo, Kim, Eun Soo, Kim, Sang-Jun, Shin, Jae-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569816/
https://www.ncbi.nlm.nih.gov/pubmed/32825401
http://dx.doi.org/10.3390/microorganisms8091265
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author Jung, YeonGyun
Tagele, Setu Bazie
Son, HyunWoo
Ibal, Jerald Conrad
Kerfahi, Dorsaf
Yun, Hyunju
Lee, Bora
Park, Clara Yongjoo
Kim, Eun Soo
Kim, Sang-Jun
Shin, Jae-Ho
author_facet Jung, YeonGyun
Tagele, Setu Bazie
Son, HyunWoo
Ibal, Jerald Conrad
Kerfahi, Dorsaf
Yun, Hyunju
Lee, Bora
Park, Clara Yongjoo
Kim, Eun Soo
Kim, Sang-Jun
Shin, Jae-Ho
author_sort Jung, YeonGyun
collection PubMed
description Environmental factors can influence the composition of gut microbiota, but understanding the combined effect of lifestyle factors on adult gut microbiota is limited. Here, we investigated whether changes in the modifiable lifestyle factors, such as cigarette smoking, alcohol consumption, sleep duration, physical exercise, and body mass index affected the gut microbiota of Korean navy trainees. The navy trainees were instructed to stop smoking and alcohol consumption and follow a sleep schedule and physical exercise regime for eight weeks. For comparison, healthy Korean civilians, who had no significant change in lifestyles for eight weeks were included in this study. A total of 208 fecal samples were collected from navy trainees (n = 66) and civilians (n = 38) at baseline and week eight. Gut flora was assessed by sequencing the highly variable region of the 16S rRNA gene. The α-and β -diversity of gut flora of both the test and control groups were not significantly changed after eight weeks. However, there was a significant difference among individuals. Smoking had a significant impact in altering α-diversity. Our study showed that a healthy lifestyle, particularly cessation of smoking, even in short periods, can affect the gut microbiome by enhancing the abundance of beneficial taxa and reducing that of harmful taxa.
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spelling pubmed-75698162020-10-27 Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change Jung, YeonGyun Tagele, Setu Bazie Son, HyunWoo Ibal, Jerald Conrad Kerfahi, Dorsaf Yun, Hyunju Lee, Bora Park, Clara Yongjoo Kim, Eun Soo Kim, Sang-Jun Shin, Jae-Ho Microorganisms Article Environmental factors can influence the composition of gut microbiota, but understanding the combined effect of lifestyle factors on adult gut microbiota is limited. Here, we investigated whether changes in the modifiable lifestyle factors, such as cigarette smoking, alcohol consumption, sleep duration, physical exercise, and body mass index affected the gut microbiota of Korean navy trainees. The navy trainees were instructed to stop smoking and alcohol consumption and follow a sleep schedule and physical exercise regime for eight weeks. For comparison, healthy Korean civilians, who had no significant change in lifestyles for eight weeks were included in this study. A total of 208 fecal samples were collected from navy trainees (n = 66) and civilians (n = 38) at baseline and week eight. Gut flora was assessed by sequencing the highly variable region of the 16S rRNA gene. The α-and β -diversity of gut flora of both the test and control groups were not significantly changed after eight weeks. However, there was a significant difference among individuals. Smoking had a significant impact in altering α-diversity. Our study showed that a healthy lifestyle, particularly cessation of smoking, even in short periods, can affect the gut microbiome by enhancing the abundance of beneficial taxa and reducing that of harmful taxa. MDPI 2020-08-20 /pmc/articles/PMC7569816/ /pubmed/32825401 http://dx.doi.org/10.3390/microorganisms8091265 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Jung, YeonGyun
Tagele, Setu Bazie
Son, HyunWoo
Ibal, Jerald Conrad
Kerfahi, Dorsaf
Yun, Hyunju
Lee, Bora
Park, Clara Yongjoo
Kim, Eun Soo
Kim, Sang-Jun
Shin, Jae-Ho
Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change
title Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change
title_full Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change
title_fullStr Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change
title_full_unstemmed Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change
title_short Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change
title_sort modulation of gut microbiota in korean navy trainees following a healthy lifestyle change
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569816/
https://www.ncbi.nlm.nih.gov/pubmed/32825401
http://dx.doi.org/10.3390/microorganisms8091265
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