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The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties

Blueberries have seen an ascending production line boosted by World Health Organization (WHO) approvals for their contributions to a healthy diet and the evidence that they act against different diseases. This increase resulted in significant amounts of discarded leaves, which could be a valuable so...

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Autores principales: Ștefănescu, Bianca-Eugenia, Călinoiu, Lavinia Florina, Ranga, Floricuța, Fetea, Florinela, Mocan, Andrei, Vodnar, Dan Cristian, Crișan, Gianina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569947/
https://www.ncbi.nlm.nih.gov/pubmed/32932659
http://dx.doi.org/10.3390/plants9091193
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author Ștefănescu, Bianca-Eugenia
Călinoiu, Lavinia Florina
Ranga, Floricuța
Fetea, Florinela
Mocan, Andrei
Vodnar, Dan Cristian
Crișan, Gianina
author_facet Ștefănescu, Bianca-Eugenia
Călinoiu, Lavinia Florina
Ranga, Floricuța
Fetea, Florinela
Mocan, Andrei
Vodnar, Dan Cristian
Crișan, Gianina
author_sort Ștefănescu, Bianca-Eugenia
collection PubMed
description Blueberries have seen an ascending production line boosted by World Health Organization (WHO) approvals for their contributions to a healthy diet and the evidence that they act against different diseases. This increase resulted in significant amounts of discarded leaves, which could be a valuable source of bioactive compounds. In the present study, ultrasound-assisted extraction technology was used to determine and compare the chemical and biological profiles of leaves from six commercial blueberry (Vaccinium corymbosum L.) varieties. Feruloylquinic acid was the major compound identified, ranging from 19.23 ± 0.18 mg/g (at the lowest level, registered in the Spartan variety) to 49.62 ± 0.41 mg/g (at the highest level, registered in the Nelson variety). Rutin was the second major compound identified, for which Toro, Nelson, and Elliot leaves registered the highest values, with 35.77 ± 0.19 mg/g, 32.50 ± 0.20 mg/g, and 31.53 ± 0.1 mg/g, respectively. Even though analogous polyphenols were detected in the six cultivars, their concentrations and amounts were different. The leaf extracts of the cultivars Toro, Elliot, and Nelson appear to be good sources of antioxidants, registering high percentage inhibitions of DPPH radicals, of 70.41%, 68.42%, and 58.69%, respectively. The blueberry leaf extracts had a strong antibacterial activity and a low antifungal capacity, and a low-to-moderate antimutagenic capacity towards Salmonella typhimurium TA98 and TA100 strains, with Toro leaf being the best candidate. All of these biological activities indicate health-related benefits, recommending them as suitable candidates for medical and pharmaceutical applications. The present paper adds significant knowledge to the field of blueberry leaves via chemical and biological profiles, supporting the ultrasound-assisted extraction technique as a useful and green method to provide alternative sources of bioactive compounds.
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spelling pubmed-75699472020-10-29 The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties Ștefănescu, Bianca-Eugenia Călinoiu, Lavinia Florina Ranga, Floricuța Fetea, Florinela Mocan, Andrei Vodnar, Dan Cristian Crișan, Gianina Plants (Basel) Article Blueberries have seen an ascending production line boosted by World Health Organization (WHO) approvals for their contributions to a healthy diet and the evidence that they act against different diseases. This increase resulted in significant amounts of discarded leaves, which could be a valuable source of bioactive compounds. In the present study, ultrasound-assisted extraction technology was used to determine and compare the chemical and biological profiles of leaves from six commercial blueberry (Vaccinium corymbosum L.) varieties. Feruloylquinic acid was the major compound identified, ranging from 19.23 ± 0.18 mg/g (at the lowest level, registered in the Spartan variety) to 49.62 ± 0.41 mg/g (at the highest level, registered in the Nelson variety). Rutin was the second major compound identified, for which Toro, Nelson, and Elliot leaves registered the highest values, with 35.77 ± 0.19 mg/g, 32.50 ± 0.20 mg/g, and 31.53 ± 0.1 mg/g, respectively. Even though analogous polyphenols were detected in the six cultivars, their concentrations and amounts were different. The leaf extracts of the cultivars Toro, Elliot, and Nelson appear to be good sources of antioxidants, registering high percentage inhibitions of DPPH radicals, of 70.41%, 68.42%, and 58.69%, respectively. The blueberry leaf extracts had a strong antibacterial activity and a low antifungal capacity, and a low-to-moderate antimutagenic capacity towards Salmonella typhimurium TA98 and TA100 strains, with Toro leaf being the best candidate. All of these biological activities indicate health-related benefits, recommending them as suitable candidates for medical and pharmaceutical applications. The present paper adds significant knowledge to the field of blueberry leaves via chemical and biological profiles, supporting the ultrasound-assisted extraction technique as a useful and green method to provide alternative sources of bioactive compounds. MDPI 2020-09-12 /pmc/articles/PMC7569947/ /pubmed/32932659 http://dx.doi.org/10.3390/plants9091193 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ștefănescu, Bianca-Eugenia
Călinoiu, Lavinia Florina
Ranga, Floricuța
Fetea, Florinela
Mocan, Andrei
Vodnar, Dan Cristian
Crișan, Gianina
The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties
title The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties
title_full The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties
title_fullStr The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties
title_full_unstemmed The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties
title_short The Chemical and Biological Profiles of Leaves from Commercial Blueberry Varieties
title_sort chemical and biological profiles of leaves from commercial blueberry varieties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569947/
https://www.ncbi.nlm.nih.gov/pubmed/32932659
http://dx.doi.org/10.3390/plants9091193
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