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Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review

Collagen (Col) is a naturally available material and is widely used in the tissue engineering and medical field owing to its high biocompatibility and malleability. Promising results on the use of Col were observed in the periodontal application and many attempts have been carried out to inculcate C...

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Autores principales: Naomi, Ruth, Ardhani, Retno, Hafiyyah, Osa Amila, Fauzi, Mh Busra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570157/
https://www.ncbi.nlm.nih.gov/pubmed/32933133
http://dx.doi.org/10.3390/polym12092081
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author Naomi, Ruth
Ardhani, Retno
Hafiyyah, Osa Amila
Fauzi, Mh Busra
author_facet Naomi, Ruth
Ardhani, Retno
Hafiyyah, Osa Amila
Fauzi, Mh Busra
author_sort Naomi, Ruth
collection PubMed
description Collagen (Col) is a naturally available material and is widely used in the tissue engineering and medical field owing to its high biocompatibility and malleability. Promising results on the use of Col were observed in the periodontal application and many attempts have been carried out to inculcate Col for gingival recession (GR). Col is found to be an excellent provisional bioscaffold for the current treatment in GR. Therefore, the aim of this paper is to scrutinize an overview of the reported Col effect focusing on in vitro, in vivo, and clinical trials in GR application. A comprehensive literature search was performed using EBSCOhost, Science Direct, Springer Link, and Medline & Ovid databases to identify the potential articles on particular topics. The search query was accomplished based on the Boolean operators involving keywords such as (1) collagen OR scaffold OR hybrid scaffold OR biomaterial AND (2) gingiva recession OR tissue regeneration OR dental tissue OR healing mechanism OR gingiva. Only articles published from 2015 onwards were selected for further analysis. This review includes the physicochemical properties of Col scaffold and the outcome for GR. The comprehensive literature search retrieved a total of 3077 articles using the appropriate keywords. However, on the basis of the inclusion and exclusion criteria, only 15 articles were chosen for further review. The results from these articles indicated that Col promoted gingival tissue regeneration for GR healing. Therefore, this systematic review recapitulated that Col enhances regeneration of gingival tissue either through a slow or rapid process with no sign of cytotoxicity or adverse effect.
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spelling pubmed-75701572020-10-28 Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review Naomi, Ruth Ardhani, Retno Hafiyyah, Osa Amila Fauzi, Mh Busra Polymers (Basel) Review Collagen (Col) is a naturally available material and is widely used in the tissue engineering and medical field owing to its high biocompatibility and malleability. Promising results on the use of Col were observed in the periodontal application and many attempts have been carried out to inculcate Col for gingival recession (GR). Col is found to be an excellent provisional bioscaffold for the current treatment in GR. Therefore, the aim of this paper is to scrutinize an overview of the reported Col effect focusing on in vitro, in vivo, and clinical trials in GR application. A comprehensive literature search was performed using EBSCOhost, Science Direct, Springer Link, and Medline & Ovid databases to identify the potential articles on particular topics. The search query was accomplished based on the Boolean operators involving keywords such as (1) collagen OR scaffold OR hybrid scaffold OR biomaterial AND (2) gingiva recession OR tissue regeneration OR dental tissue OR healing mechanism OR gingiva. Only articles published from 2015 onwards were selected for further analysis. This review includes the physicochemical properties of Col scaffold and the outcome for GR. The comprehensive literature search retrieved a total of 3077 articles using the appropriate keywords. However, on the basis of the inclusion and exclusion criteria, only 15 articles were chosen for further review. The results from these articles indicated that Col promoted gingival tissue regeneration for GR healing. Therefore, this systematic review recapitulated that Col enhances regeneration of gingival tissue either through a slow or rapid process with no sign of cytotoxicity or adverse effect. MDPI 2020-09-13 /pmc/articles/PMC7570157/ /pubmed/32933133 http://dx.doi.org/10.3390/polym12092081 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Naomi, Ruth
Ardhani, Retno
Hafiyyah, Osa Amila
Fauzi, Mh Busra
Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review
title Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review
title_full Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review
title_fullStr Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review
title_full_unstemmed Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review
title_short Current Insight of Collagen Biomatrix for Gingival Recession: An Evidence-Based Systematic Review
title_sort current insight of collagen biomatrix for gingival recession: an evidence-based systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570157/
https://www.ncbi.nlm.nih.gov/pubmed/32933133
http://dx.doi.org/10.3390/polym12092081
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