Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity

Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (1–3), were isolated from the white flowers of Impatiens balsamina. The structures of these phytochemical constituents (1–3) were elucidated through 1D and 2D Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data analyses...

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Autores principales: Lee, Tae Hyun, Suh, Won Se, Subedi, Lalita, Kim, Sun Yeou, Choi, Sang Un, Lee, Kang Ro, Kim, Chung Sub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570163/
https://www.ncbi.nlm.nih.gov/pubmed/32846890
http://dx.doi.org/10.3390/plants9091083
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author Lee, Tae Hyun
Suh, Won Se
Subedi, Lalita
Kim, Sun Yeou
Choi, Sang Un
Lee, Kang Ro
Kim, Chung Sub
author_facet Lee, Tae Hyun
Suh, Won Se
Subedi, Lalita
Kim, Sun Yeou
Choi, Sang Un
Lee, Kang Ro
Kim, Chung Sub
author_sort Lee, Tae Hyun
collection PubMed
description Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (1–3), were isolated from the white flowers of Impatiens balsamina. The structures of these phytochemical constituents (1–3) were elucidated through 1D and 2D Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data analyses followed by chemical methods. All the characterized compounds (1–3) were evaluated for their antiproliferative activity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and BT549) and their anti-neuroinflammatory activity on the basis of inhibition levels of nitric oxide (NO) in the lipopolysaccharide (LPS)-stimulated murine microglia BV-2 cell lines.
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spelling pubmed-75701632020-10-28 Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity Lee, Tae Hyun Suh, Won Se Subedi, Lalita Kim, Sun Yeou Choi, Sang Un Lee, Kang Ro Kim, Chung Sub Plants (Basel) Article Three new oleanane-type triterpenoidal glycosides, imbalosides A–C (1–3), were isolated from the white flowers of Impatiens balsamina. The structures of these phytochemical constituents (1–3) were elucidated through 1D and 2D Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) data analyses followed by chemical methods. All the characterized compounds (1–3) were evaluated for their antiproliferative activity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and BT549) and their anti-neuroinflammatory activity on the basis of inhibition levels of nitric oxide (NO) in the lipopolysaccharide (LPS)-stimulated murine microglia BV-2 cell lines. MDPI 2020-08-24 /pmc/articles/PMC7570163/ /pubmed/32846890 http://dx.doi.org/10.3390/plants9091083 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Tae Hyun
Suh, Won Se
Subedi, Lalita
Kim, Sun Yeou
Choi, Sang Un
Lee, Kang Ro
Kim, Chung Sub
Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity
title Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity
title_full Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity
title_fullStr Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity
title_full_unstemmed Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity
title_short Three New Oleanane-Type Triterpenoidal Glycosides from Impatiens balsamina and Their Biological Activity
title_sort three new oleanane-type triterpenoidal glycosides from impatiens balsamina and their biological activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570163/
https://www.ncbi.nlm.nih.gov/pubmed/32846890
http://dx.doi.org/10.3390/plants9091083
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