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Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis

Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated necroptosis is a key driver of acute lung injury during bacterial pneumonia. Her...

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Detalles Bibliográficos
Autores principales: Gonzalez-Juarbe, Norberto, Riegler, Ashleigh N., Jureka, Alexander S., Gilley, Ryan P., Brand, Jeffrey D., Trombley, John E., Scott, Ninecia R., Platt, Maryann P., Dube, Peter H., Petit, Chad M., Harrod, Kevin S., Orihuela, Carlos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570217/
https://www.ncbi.nlm.nih.gov/pubmed/32846120
http://dx.doi.org/10.1016/j.celrep.2020.108062