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Influenza-Induced Oxidative Stress Sensitizes Lung Cells to Bacterial-Toxin-Mediated Necroptosis
Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated necroptosis is a key driver of acute lung injury during bacterial pneumonia. Her...
Autores principales: | Gonzalez-Juarbe, Norberto, Riegler, Ashleigh N., Jureka, Alexander S., Gilley, Ryan P., Brand, Jeffrey D., Trombley, John E., Scott, Ninecia R., Platt, Maryann P., Dube, Peter H., Petit, Chad M., Harrod, Kevin S., Orihuela, Carlos J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570217/ https://www.ncbi.nlm.nih.gov/pubmed/32846120 http://dx.doi.org/10.1016/j.celrep.2020.108062 |
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