Cargando…
Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound
Background. Congenital urethral obstruction occurs most frequently as a result of urethral valves. The diagnosis is usually confirmed pre- or neonatally. Though not ideal, delayed diagnosis can occur in childhood, adolescence, or adulthood. Despite a normal prenatal ultrasound, there may still be a...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570289/ https://www.ncbi.nlm.nih.gov/pubmed/33117862 http://dx.doi.org/10.1177/2333794X20958918 |
_version_ | 1783596914636226560 |
---|---|
author | Shields, Lisa B. E. White, Jeffrey T. Mohamed, Ahmad Z. Peppas, Dennis S. Rosenberg, Eran |
author_facet | Shields, Lisa B. E. White, Jeffrey T. Mohamed, Ahmad Z. Peppas, Dennis S. Rosenberg, Eran |
author_sort | Shields, Lisa B. E. |
collection | PubMed |
description | Background. Congenital urethral obstruction occurs most frequently as a result of urethral valves. The diagnosis is usually confirmed pre- or neonatally. Though not ideal, delayed diagnosis can occur in childhood, adolescence, or adulthood. Despite a normal prenatal ultrasound, there may still be a delayed diagnosis of urethral valves. Methods. We present 4 patients with delayed diagnosis of posterior urethral valves (PUV) and 1 patient with delayed diagnosis of anterior urethral valves (AUV) who were evaluated by a pediatric urologist at our Institution. We determined the age and symptoms at presentation, physical examination, micturating cystourethrogram (MCU) findings prior to the valve ablation, renal function before and after valve ablation, type of valve ablation, and urine culture and sensitivity. The urological courses following urethral valve ablation including urodynamic study findings are described. Results. The median age at presentation was 33 months. All 5 patients presented with decreased urine output and urinary retention. All 5 patients underwent a MCU that demonstrated bladder trabeculations (3 cases), vesicoureteral reflux (3 cases), and bladder diverticula (2 cases). A urethral valve ablation was performed in all cases. Four patients underwent a renal function panel prior to this procedure, and their serum BUN/creatinine levels decreased 1 day postoperatively. Conclusion. Pediatricians should consider urethral valves as causing urethral obstruction although the prenatal ultrasound may be normal. Early diagnosis and prompt treatment of urethral valves may mitigate the potentially devastating morbidities such as renal failure, congestive heart failure, and respiratory distress that may ensue. |
format | Online Article Text |
id | pubmed-7570289 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-75702892020-10-27 Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound Shields, Lisa B. E. White, Jeffrey T. Mohamed, Ahmad Z. Peppas, Dennis S. Rosenberg, Eran Glob Pediatr Health Original Article Background. Congenital urethral obstruction occurs most frequently as a result of urethral valves. The diagnosis is usually confirmed pre- or neonatally. Though not ideal, delayed diagnosis can occur in childhood, adolescence, or adulthood. Despite a normal prenatal ultrasound, there may still be a delayed diagnosis of urethral valves. Methods. We present 4 patients with delayed diagnosis of posterior urethral valves (PUV) and 1 patient with delayed diagnosis of anterior urethral valves (AUV) who were evaluated by a pediatric urologist at our Institution. We determined the age and symptoms at presentation, physical examination, micturating cystourethrogram (MCU) findings prior to the valve ablation, renal function before and after valve ablation, type of valve ablation, and urine culture and sensitivity. The urological courses following urethral valve ablation including urodynamic study findings are described. Results. The median age at presentation was 33 months. All 5 patients presented with decreased urine output and urinary retention. All 5 patients underwent a MCU that demonstrated bladder trabeculations (3 cases), vesicoureteral reflux (3 cases), and bladder diverticula (2 cases). A urethral valve ablation was performed in all cases. Four patients underwent a renal function panel prior to this procedure, and their serum BUN/creatinine levels decreased 1 day postoperatively. Conclusion. Pediatricians should consider urethral valves as causing urethral obstruction although the prenatal ultrasound may be normal. Early diagnosis and prompt treatment of urethral valves may mitigate the potentially devastating morbidities such as renal failure, congestive heart failure, and respiratory distress that may ensue. SAGE Publications 2020-10-15 /pmc/articles/PMC7570289/ /pubmed/33117862 http://dx.doi.org/10.1177/2333794X20958918 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Shields, Lisa B. E. White, Jeffrey T. Mohamed, Ahmad Z. Peppas, Dennis S. Rosenberg, Eran Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound |
title | Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound |
title_full | Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound |
title_fullStr | Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound |
title_full_unstemmed | Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound |
title_short | Delayed Presentation of Urethral Valves: A Diagnosis That Should Be Suspected Despite a Normal Prenatal Ultrasound |
title_sort | delayed presentation of urethral valves: a diagnosis that should be suspected despite a normal prenatal ultrasound |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570289/ https://www.ncbi.nlm.nih.gov/pubmed/33117862 http://dx.doi.org/10.1177/2333794X20958918 |
work_keys_str_mv | AT shieldslisabe delayedpresentationofurethralvalvesadiagnosisthatshouldbesuspecteddespiteanormalprenatalultrasound AT whitejeffreyt delayedpresentationofurethralvalvesadiagnosisthatshouldbesuspecteddespiteanormalprenatalultrasound AT mohamedahmadz delayedpresentationofurethralvalvesadiagnosisthatshouldbesuspecteddespiteanormalprenatalultrasound AT peppasdenniss delayedpresentationofurethralvalvesadiagnosisthatshouldbesuspecteddespiteanormalprenatalultrasound AT rosenbergeran delayedpresentationofurethralvalvesadiagnosisthatshouldbesuspecteddespiteanormalprenatalultrasound |