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A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male

Vasculitis is an inflammatory process involving blood vessels of various sizes, including the small vessels in the kidneys to the large vessels, such as the aorta. This inflammatory condition is usually autoimmune in nature and is associated with involvement of many locations, such as the sinuses, l...

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Autores principales: Civelli, Valerie F., Narang, Vishal K., Sharma, Rupam, Sharma, Ritika, Kim, Jessica, Bhandohal, Janpreet, Moosavi, Leila, Cobos, Everardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570297/
https://www.ncbi.nlm.nih.gov/pubmed/33054423
http://dx.doi.org/10.1177/2324709620966855
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author Civelli, Valerie F.
Narang, Vishal K.
Sharma, Rupam
Sharma, Ritika
Kim, Jessica
Bhandohal, Janpreet
Moosavi, Leila
Cobos, Everardo
author_facet Civelli, Valerie F.
Narang, Vishal K.
Sharma, Rupam
Sharma, Ritika
Kim, Jessica
Bhandohal, Janpreet
Moosavi, Leila
Cobos, Everardo
author_sort Civelli, Valerie F.
collection PubMed
description Vasculitis is an inflammatory process involving blood vessels of various sizes, including the small vessels in the kidneys to the large vessels, such as the aorta. This inflammatory condition is usually autoimmune in nature and is associated with involvement of many locations, such as the sinuses, lungs, kidneys, and even the heart. Specifically, eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis that may initially hide as asthma, allergic rhinitis, and/or sinusitis. However, it is known to become a lethal disease once progressed to include cardiovascular manifestations. It is important to remember EGPA as a differential for any patient with a history of asthma, allergic rhinitis, and/or sinusitis who also presents with cardiovascular complaints and eosinophilia. Treatment recommendations focus on immunosuppression in such cases. In this article, we discuss the case of a 62-year-old male, with a known history of asthma, who presented to the emergency department with concern for his chest pain and right-sided weakness. He was later diagnosed with EGPA with eosinophilic myocarditis. Diagnosis and treatment are described.
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spelling pubmed-75702972020-10-27 A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male Civelli, Valerie F. Narang, Vishal K. Sharma, Rupam Sharma, Ritika Kim, Jessica Bhandohal, Janpreet Moosavi, Leila Cobos, Everardo J Investig Med High Impact Case Rep Case Report Vasculitis is an inflammatory process involving blood vessels of various sizes, including the small vessels in the kidneys to the large vessels, such as the aorta. This inflammatory condition is usually autoimmune in nature and is associated with involvement of many locations, such as the sinuses, lungs, kidneys, and even the heart. Specifically, eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic vasculitis that may initially hide as asthma, allergic rhinitis, and/or sinusitis. However, it is known to become a lethal disease once progressed to include cardiovascular manifestations. It is important to remember EGPA as a differential for any patient with a history of asthma, allergic rhinitis, and/or sinusitis who also presents with cardiovascular complaints and eosinophilia. Treatment recommendations focus on immunosuppression in such cases. In this article, we discuss the case of a 62-year-old male, with a known history of asthma, who presented to the emergency department with concern for his chest pain and right-sided weakness. He was later diagnosed with EGPA with eosinophilic myocarditis. Diagnosis and treatment are described. SAGE Publications 2020-10-15 /pmc/articles/PMC7570297/ /pubmed/33054423 http://dx.doi.org/10.1177/2324709620966855 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Civelli, Valerie F.
Narang, Vishal K.
Sharma, Rupam
Sharma, Ritika
Kim, Jessica
Bhandohal, Janpreet
Moosavi, Leila
Cobos, Everardo
A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male
title A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male
title_full A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male
title_fullStr A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male
title_full_unstemmed A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male
title_short A Progressive Case of Eosinophilic Myocarditis Due to Eosinophilic Granulomatosis With Polyangiitis in a Caucasian Male
title_sort progressive case of eosinophilic myocarditis due to eosinophilic granulomatosis with polyangiitis in a caucasian male
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570297/
https://www.ncbi.nlm.nih.gov/pubmed/33054423
http://dx.doi.org/10.1177/2324709620966855
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