AlignmentViewer: Sequence Analysis of Large Protein Families

AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space....

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Detalles Bibliográficos
Autores principales: Reguant, Roc, Antipin, Yevgeniy, Sheridan, Rob, Dallago, Christian, Diamantoukos, Drew, Luna, Augustin, Sander, Chris, Gauthier, Nicholas Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Software Tool Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570326/
https://www.ncbi.nlm.nih.gov/pubmed/33123346
http://dx.doi.org/10.12688/f1000research.22242.2
Descripción
Sumario:AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space. The tool is directly accessible in web browsers without the need for software installation. It can handle protein families with tens of thousands of sequences and is particularly suitable for evolutionary coupling analysis, e.g. via EVcouplings.org.

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