AlignmentViewer: Sequence Analysis of Large Protein Families

AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space....

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Autores principales: Reguant, Roc, Antipin, Yevgeniy, Sheridan, Rob, Dallago, Christian, Diamantoukos, Drew, Luna, Augustin, Sander, Chris, Gauthier, Nicholas Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2020
Materias:
Software Tool Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570326/
https://www.ncbi.nlm.nih.gov/pubmed/33123346
http://dx.doi.org/10.12688/f1000research.22242.2
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author Reguant, Roc
Antipin, Yevgeniy
Sheridan, Rob
Dallago, Christian
Diamantoukos, Drew
Luna, Augustin
Sander, Chris
Gauthier, Nicholas Paul
author_facet Reguant, Roc
Antipin, Yevgeniy
Sheridan, Rob
Dallago, Christian
Diamantoukos, Drew
Luna, Augustin
Sander, Chris
Gauthier, Nicholas Paul
author_sort Reguant, Roc
collection PubMed
description AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space. The tool is directly accessible in web browsers without the need for software installation. It can handle protein families with tens of thousands of sequences and is particularly suitable for evolutionary coupling analysis, e.g. via EVcouplings.org.
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spelling pubmed-75703262020-10-28 AlignmentViewer: Sequence Analysis of Large Protein Families Reguant, Roc Antipin, Yevgeniy Sheridan, Rob Dallago, Christian Diamantoukos, Drew Luna, Augustin Sander, Chris Gauthier, Nicholas Paul F1000Res Software Tool Article AlignmentViewer is a web-based tool to view and analyze multiple sequence alignments of protein families. The particular strengths of AlignmentViewer include flexible visualization at different scales as well as analysis of conservation patterns and of the distribution of proteins in sequence space. The tool is directly accessible in web browsers without the need for software installation. It can handle protein families with tens of thousands of sequences and is particularly suitable for evolutionary coupling analysis, e.g. via EVcouplings.org. F1000 Research Limited 2020-10-15 /pmc/articles/PMC7570326/ /pubmed/33123346 http://dx.doi.org/10.12688/f1000research.22242.2 Text en Copyright: © 2020 Reguant R et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Software Tool Article
Reguant, Roc
Antipin, Yevgeniy
Sheridan, Rob
Dallago, Christian
Diamantoukos, Drew
Luna, Augustin
Sander, Chris
Gauthier, Nicholas Paul
AlignmentViewer: Sequence Analysis of Large Protein Families
title AlignmentViewer: Sequence Analysis of Large Protein Families
title_full AlignmentViewer: Sequence Analysis of Large Protein Families
title_fullStr AlignmentViewer: Sequence Analysis of Large Protein Families
title_full_unstemmed AlignmentViewer: Sequence Analysis of Large Protein Families
title_short AlignmentViewer: Sequence Analysis of Large Protein Families
title_sort alignmentviewer: sequence analysis of large protein families
topic Software Tool Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570326/
https://www.ncbi.nlm.nih.gov/pubmed/33123346
http://dx.doi.org/10.12688/f1000research.22242.2
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