Cargando…

Diabetes Leads to Alterations in Normal Metabolic Transitions of Pregnancy as Revealed by Time-Course Metabolomics

Women with diabetes during pregnancy are at increased risk of poor maternal and neonatal outcomes. Despite this, the effects of pre-gestational (PGDM) or gestational diabetes (GDM) on metabolism during pregnancy are not well understood. In this study, we utilized metabolomics to identify serum metab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Walejko, Jacquelyn M., Chelliah, Anushka, Keller-Wood, Maureen, Wasserfall, Clive, Atkinson, Mark, Gregg, Anthony, Edison, Arthur S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570364/ https://www.ncbi.nlm.nih.gov/pubmed/32867274 http://dx.doi.org/10.3390/metabo10090350

Ejemplares similares

Global Metabolomics of the Placenta Reveals Distinct Metabolic Profiles between Maternal and Fetal Placental Tissues Following Delivery in Non-Labored Women
por: Walejko, Jacquelyn M., et al.
Publicado: (2018)

Integrated Metabolomics and Transcriptomics Suggest the Global Metabolic Response to 2-Aminoacrylate Stress in Salmonella enterica
por: Borchert, Andrew J., et al.
Publicado: (2019)

Untargeted metabolomic analysis in naturally occurring canine diabetes mellitus identifies similarities to human Type 1 Diabetes
por: O’Kell, Allison L., et al.
Publicado: (2017)

Taking a Daily Vitamin to Prevent Type 1 Diabetes?
por: Wasserfall, Clive, et al.
Publicado: (2009)

NOREVA: enhanced normalization and evaluation of time-course and multi-class metabolomic data
por: Yang, Qingxia, et al.
Publicado: (2020)

Synchronization of the Normal Human Peripheral Immune System: A Comprehensive Circadian Systems Immunology Analysis
por: Beam, Craig A., et al.
Publicado: (2020)

Central Role for Interleukin-2 in Type 1 Diabetes
por: Hulme, Maigan A., et al.
Publicado: (2012)

Vitamin D Levels in Subjects With and Without Type 1 Diabetes Residing in a Solar Rich Environment
por: Bierschenk, Lindsey, et al.
Publicado: (2009)

Metabolomics of Human Amniotic Fluid and Maternal Plasma during Normal Pregnancy
por: Orczyk-Pawilowicz, Magdalena, et al.
Publicado: (2016)

Changes of lipoxin levels during pregnancy and the monthly-cycle, condition the normal course of pregnancy or pathology
por: Szczuko, Małgorzata, et al.
Publicado: (2020)

Evaluation for type 1 diabetes associated autoantibodies in diabetic and non-diabetic Australian terriers and Samoyeds
por: O’Kell, Allison L., et al.
Publicado: (2020)

Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice
por: Suarez-Pinzon, Wilma L., et al.
Publicado: (2008)

Increased Complement Activation in Human Type 1 Diabetes Pancreata
por: Rowe, Patrick, et al.
Publicado: (2013)

Influence of Membrane CD25 Stability on T Lymphocyte Activity: Implications for Immunoregulation
por: Brusko, Todd M., et al.
Publicado: (2009)

The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus
por: Lantow, Margareta, et al.
Publicado: (2013)

Exocrine and Endocrine Inflammation Increases Cellular Replication in the Pancreatic Duct Compartment in Type 1 Diabetes
por: Kulkarni, Shweta, et al.
Publicado: (2022)

Endocannabinoid Metabolome Characterization of Transitional and Mature Human Milk
por: Gaitán, Adriana V., et al.
Publicado: (2018)

Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
por: Campbell-Thompson, Martha, et al.
Publicado: (2016)

Plant-based vaccines for oral delivery of type 1 diabetes-related autoantigens: Evaluating oral tolerance mechanisms and disease prevention in NOD mice
por: Posgai, Amanda L., et al.
Publicado: (2017)

(13)C Metabolomics: NMR and IROA for Unknown Identification
por: Clendinen, Chaevien S., et al.
Publicado: (2016)

Regulated hAAT Expression from a Novel rAAV Vector and Its Application in the Prevention of Type 1 Diabetes
por: Ma, Hongxia, et al.
Publicado: (2019)

339 A serum exocrine enzyme as a biomarker of response to immunotherapy in type 1 diabetes.
por: Bruggeman, Brittany S, et al.
Publicado: (2022)

Typical course of cystinuria leading to untypical complications in pregnancy: A case report and review of literature
por: Ivandic, Ema, et al.
Publicado: (2023)

NMR in Metabolomics and Natural Products Research: Two Sides of the Same Coin
por: Robinette, Steven L., et al.
Publicado: (2011)

Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis
por: Boddy, Sarah, et al.
Publicado: (2022)

Membrane marker selection for segmenting single cell spatial proteomics data
por: Dayao, Monica T., et al.
Publicado: (2022)

Machine learning approaches to predict gestational age in normal and complicated pregnancies via urinary metabolomics analysis
por: Yamauchi, Takafumi, et al.
Publicado: (2021)

Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked?
por: O’Kell, Allison L., et al.
Publicado: (2017)

Alternatives to Nuclear Overhauser Enhancement Spectroscopy Presat and Carr–Purcell–Meiboom–Gill Presat for NMR-Based Metabolomics
por: Le Guennec, Adrien, et al.
Publicado: (2017)

Metabolomics and Natural-Products Strategies to Study Chemical Ecology in Nematodes
por: Edison, Arthur S., et al.
Publicado: (2015)

Metabolomics Data Normalization with EigenMS
por: Karpievitch, Yuliya V., et al.
Publicado: (2014)

UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures
por: Ramani, Shilpa, et al.
Publicado: (2007)

A combination hydrogel microparticle-based vaccine prevents type 1 diabetes in non-obese diabetic mice
por: Yoon, Young Mee, et al.
Publicado: (2015)

Exploration of autoantibody responses in canine diabetes using protein arrays
por: O’Kell, Allison L., et al.
Publicado: (2022)

Elemental Metabolomics and Pregnancy Outcomes
por: McKeating, Daniel R., et al.
Publicado: (2019)

Optimizing multiplexed imaging experimental design through tissue spatial segregation estimation
por: Bost, Pierre, et al.
Publicado: (2022)

Utilization of leadless pacemaker following transvenous lead extraction: A series of 10 successful cases
por: Tay, Kokhoon, et al.
Publicado: (2022)

The clinical course of COVID in pregnancy
por: Syeda, Sbaa, et al.
Publicado: (2020)

The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice
por: Davoodi-Semiromi, Abdoreza, et al.
Publicado: (2012)

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model
por: Grimstein, Christian, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_624c7vohm5vad00ldknptvu2cq