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A New Co-Crystal of Synthetic Drug Rosiglitazone with Natural Medicine Berberine: Preparation, Crystal Structures, and Dissolution

A co-crystal of rosiglitazone (Rsg) with berberine (Bbr), Rsg-Bbr, was prepared by the solvent evaporation method and characterized. The results showed that the electrostatic attraction existed between the nitrogen anion of rosiglitazone and the quaternary ammonium cation of berberine, and C-H···O h...

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Detalles Bibliográficos
Autores principales: Guan, Xiaoshu, Jiang, Lan, Cai, Linhong, Zhang, Li, Hu, Xiangnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570454/
https://www.ncbi.nlm.nih.gov/pubmed/32962058
http://dx.doi.org/10.3390/molecules25184288