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Heparan Sulfate Proteoglycans Biosynthesis and Post Synthesis Mechanisms Combine Few Enzymes and Few Core Proteins to Generate Extensive Structural and Functional Diversity

Glycosylation is a common and widespread post-translational modification that affects a large majority of proteins. Of these, a small minority, about 20, are specifically modified by the addition of heparan sulfate, a linear polysaccharide from the glycosaminoglycan family. The resulting molecules,...

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Detalles Bibliográficos
Autores principales: Annaval, Thibault, Wild, Rebekka, Crétinon, Yoann, Sadir, Rabia, Vivès, Romain R., Lortat-Jacob, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570499/
https://www.ncbi.nlm.nih.gov/pubmed/32937952
http://dx.doi.org/10.3390/molecules25184215