Novel Bis-Ammonium Salts of Pyridoxine: Synthesis and Antimicrobial Properties

A series of 108 novel quaternary bis-ammonium pyridoxine derivatives carrying various substituents at the quaternary nitrogen’s and acetal carbon was synthesized. Thirteen compounds exhibited antibacterial and antifungal activity (minimum inhibitory concentration (MIC) 0.25–16 µg/mL) comparable or s...

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Detalles Bibliográficos
Autores principales: Shtyrlin, Nikita V., Pugachev, Mikhail V., Sapozhnikov, Sergey V., Garipov, Marsel R., Vafina, Rusalia M., Grishaev, Denis Y., Pavelyev, Roman S., Kazakova, Renata R., Agafonova, Mariya N., Iksanova, Alfiya G., Lisovskaya, Svetlana A., Zeldi, Marina I., Krylova, Elena S., Nikitina, Elena V., Sabirova, Alina E., Kayumov, Airat R., Shtyrlin, Yurii G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570726/
https://www.ncbi.nlm.nih.gov/pubmed/32971844
http://dx.doi.org/10.3390/molecules25184341

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