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Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility

β-carotene is a promising natural active ingredient for optimum human health. However, the insolubility in water, low oral bioavailability, and instability in oxygen, heat, and light are key factors to limit its application as incorporation into functional foods. Therefore, gliadin nanoparticles (GN...

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Detalles Bibliográficos
Autores principales: Cheng, Ce, Gao, Yi, Wu, Zhihua, Miao, Jinyu, Gao, Hongxia, Ma, Li, Zou, Liqiang, Peng, Shengfeng, Liu, Chengmei, Liu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570780/
https://www.ncbi.nlm.nih.gov/pubmed/32932691
http://dx.doi.org/10.3390/molecules25184188
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author Cheng, Ce
Gao, Yi
Wu, Zhihua
Miao, Jinyu
Gao, Hongxia
Ma, Li
Zou, Liqiang
Peng, Shengfeng
Liu, Chengmei
Liu, Wei
author_facet Cheng, Ce
Gao, Yi
Wu, Zhihua
Miao, Jinyu
Gao, Hongxia
Ma, Li
Zou, Liqiang
Peng, Shengfeng
Liu, Chengmei
Liu, Wei
author_sort Cheng, Ce
collection PubMed
description β-carotene is a promising natural active ingredient for optimum human health. However, the insolubility in water, low oral bioavailability, and instability in oxygen, heat, and light are key factors to limit its application as incorporation into functional foods. Therefore, gliadin nanoparticles (GNPs) Pickering emulgels were chosen as food-grade β-carotene delivery systems. The objectives of the present study were to investigate the influence of GNPs concentration on the rheological properties, stability, and simulated gastrointestinal fate of β-carotene of Pickering emulgels. The formulations of Pickering emulgels at low GNPs concentration had better fluidity, whereas at high GNPs concentration, they had stronger gel structures. Furthermore, the thermal stability of β-carotene loaded in Pickering emulgels after two pasteurization treatments was significantly improved with the increase of GNPs concentration. The Pickering emulgels stabilized with higher GNPs concentration could improve the protection and bioaccessibility of β-carotene after different storage conditions. This study demonstrated the tremendous potential of GNPs Pickering emulgels to carry β-carotene.
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spelling pubmed-75707802020-10-28 Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility Cheng, Ce Gao, Yi Wu, Zhihua Miao, Jinyu Gao, Hongxia Ma, Li Zou, Liqiang Peng, Shengfeng Liu, Chengmei Liu, Wei Molecules Article β-carotene is a promising natural active ingredient for optimum human health. However, the insolubility in water, low oral bioavailability, and instability in oxygen, heat, and light are key factors to limit its application as incorporation into functional foods. Therefore, gliadin nanoparticles (GNPs) Pickering emulgels were chosen as food-grade β-carotene delivery systems. The objectives of the present study were to investigate the influence of GNPs concentration on the rheological properties, stability, and simulated gastrointestinal fate of β-carotene of Pickering emulgels. The formulations of Pickering emulgels at low GNPs concentration had better fluidity, whereas at high GNPs concentration, they had stronger gel structures. Furthermore, the thermal stability of β-carotene loaded in Pickering emulgels after two pasteurization treatments was significantly improved with the increase of GNPs concentration. The Pickering emulgels stabilized with higher GNPs concentration could improve the protection and bioaccessibility of β-carotene after different storage conditions. This study demonstrated the tremendous potential of GNPs Pickering emulgels to carry β-carotene. MDPI 2020-09-12 /pmc/articles/PMC7570780/ /pubmed/32932691 http://dx.doi.org/10.3390/molecules25184188 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Cheng, Ce
Gao, Yi
Wu, Zhihua
Miao, Jinyu
Gao, Hongxia
Ma, Li
Zou, Liqiang
Peng, Shengfeng
Liu, Chengmei
Liu, Wei
Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility
title Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility
title_full Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility
title_fullStr Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility
title_full_unstemmed Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility
title_short Gliadin Nanoparticles Pickering Emulgels for β-Carotene Delivery: Effect of Particle Concentration on the Stability and Bioaccessibility
title_sort gliadin nanoparticles pickering emulgels for β-carotene delivery: effect of particle concentration on the stability and bioaccessibility
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570780/
https://www.ncbi.nlm.nih.gov/pubmed/32932691
http://dx.doi.org/10.3390/molecules25184188
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