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Chiral Recognition of Flexible Melatonin Receptor Ligands Induced by Conformational Equilibria
N-anilinoethylamides are a class of melatoninergic agents with the aniline portion mimicking the indole ring of the natural ligand and the ethylamide chain reproducing that of melatonin. The simplest compound in this class, N-{2-[(3-methoxyphenyl)methylamino]ethyl}acetamide (UCM793), has nanomolar b...
Autores principales: | Elisi, Gian Marco, Bedini, Annalida, Scalvini, Laura, Carmi, Caterina, Bartolucci, Silvia, Lucini, Valeria, Scaglione, Francesco, Mor, Marco, Rivara, Silvia, Spadoni, Gilberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570888/ https://www.ncbi.nlm.nih.gov/pubmed/32899888 http://dx.doi.org/10.3390/molecules25184057 |
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