High-Resolution Mass Spectrometry-Based Approaches for the Detection and Quantification of Peptidase Activity in Plasma

Proteomic technologies have identified 234 peptidases in plasma but little quantitative information about the proteolytic activity has been uncovered. In this study, the substrate profile of plasma proteases was evaluated using two nano-LC-ESI-MS/MS methods. Multiplex substrate profiling by mass spe...

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Detalles Bibliográficos
Autores principales: Maffioli, Elisa, Jiang, Zhenze, Nonnis, Simona, Negri, Armando, Romeo, Valentina, Lietz, Christopher B., Hook, Vivian, Ristagno, Giuseppe, Baselli, Giuseppe, Kistler, Erik B., Aletti, Federico, O’Donoghue, Anthony J., Tedeschi, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571063/
https://www.ncbi.nlm.nih.gov/pubmed/32899982
http://dx.doi.org/10.3390/molecules25184071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571063/
https://www.ncbi.nlm.nih.gov/pubmed/32899982
http://dx.doi.org/10.3390/molecules25184071

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