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Biased Opioid Antagonists as Modulators of Opioid Dependence: Opportunities to Improve Pain Therapy and Opioid Use Management

Opioid analgesics are effective pain therapeutics but they cause various adverse effects and addiction. For safer pain therapy, biased opioid agonists selectively target distinct μ opioid receptor (MOR) conformations, while the potential of biased opioid antagonists has been neglected. Agonists conv...

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Detalles Bibliográficos
Autores principales:	Sadee, Wolfgang, Oberdick, John, Wang, Zaijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571197/ https://www.ncbi.nlm.nih.gov/pubmed/32932935 http://dx.doi.org/10.3390/molecules25184163

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