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Metformin prevents the development of monocrotaline-induced pulmonary hypertension by decreasing serum levels of big endothelin-1
Pulmonary hypertension (PH) is a disease with poor prognosis, and it is characterized by the progressive elevation of pulmonary vascular resistance and pressure. Various factors are associated with the pathology of PH, including AMP-activated protein kinase (AMPK) deficiency. The present study aimed...
Autores principales: | Yoshida, Tomohiko, Matsuura, Katsuhiro, Goya, Seijirow, Ma, Danfu, Shimada, Kazumi, Kitpipatkun, Pitipat, Namiki, Ryosuke, Uemura, Akiko, Suzuki, Kazuhiko, Tanaka, Ryou |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571338/ https://www.ncbi.nlm.nih.gov/pubmed/33093887 http://dx.doi.org/10.3892/etm.2020.9278 |
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