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Long-term safety of sarilumab in rheumatoid arthritis: an integrated analysis with up to 7 years’ follow-up

OBJECTIVE: Sarilumab is a human monoclonal antibody that blocks IL-6 from binding to membrane-bound and soluble IL-6 receptor-α. We assessed the long-term safety of sarilumab in patients from eight clinical trials and their open-label extensions. METHODS: Data were pooled from patients with rheumato...

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Detalles Bibliográficos
Autores principales: Fleischmann, Roy, Genovese, Mark C, Lin, Yong, St John, Gregory, van der Heijde, Désirée, Wang, Sheldon, Gomez-Reino, Juan Jose, Maldonado-Cocco, Jose Antonio, Stanislav, Marina, Kivitz, Alan J, Burmester, Gerd R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571482/
https://www.ncbi.nlm.nih.gov/pubmed/31312844
http://dx.doi.org/10.1093/rheumatology/kez265