Cargando…

Mechanisms of NLRP3 priming in inflammaging and age related diseases

The NLRP3 inflammasome is a vital part of the innate immune response, whilst its aberrant activation drives the progression of a number of non-communicable diseases. Thus, NLRP3 inflammasome assembly must be tightly controlled at several checkpoints. The priming step of NLRP3 inflammasome activation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gritsenko, Anna, Green, Jack P., Brough, David, Lopez-Castejon, Gloria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571497/ https://www.ncbi.nlm.nih.gov/pubmed/32883606 http://dx.doi.org/10.1016/j.cytogfr.2020.08.003

Ejemplares similares

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
por: Gritsenko, Anna, et al.
Publicado: (2020)

Corrigendum: Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
por: Gritsenko, Anna, et al.
Publicado: (2021)

NLRP3-Inflammasome Activating DAMPs Stimulate an Inflammatory Response in Glia in the Absence of Priming Which Contributes to Brain Inflammation after Injury
por: Savage, Catherine Diane, et al.
Publicado: (2012)

Bafilomycin A1 enhances NLRP3 inflammasome activation in human monocytes independent of lysosomal acidification
por: Yu, Shi, et al.
Publicado: (2020)

NLRP3 inflammasome triggers interleukin‐37 release from human monocytes
por: Gritsenko, Anna, et al.
Publicado: (2022)

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
por: Palazón‐Riquelme, Pablo, et al.
Publicado: (2018)

Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages
por: Hoyle, Christopher, et al.
Publicado: (2022)

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages
por: Luheshi, Nadia M, et al.
Publicado: (2012)

The NLRP3–inflammasome as a sensor of organelle dysfunction
por: Seoane, Paula I., et al.
Publicado: (2020)

The NLRP3 Inflammasome: Metabolic Regulation and Contribution to Inflammaging
por: Meyers, Allison K., et al.
Publicado: (2020)

Understanding the mechanism of IL-1β secretion
por: Lopez-Castejon, Gloria, et al.
Publicado: (2011)

The NLRP3 Inflammasome as a Critical Actor in the Inflammaging Process
por: Sebastian-Valverde, Maria, et al.
Publicado: (2020)

Cellular Senescence and Inflammaging in Age-Related Diseases
por: Olivieri, Fabiola, et al.
Publicado: (2018)

Age-related cerebral small vessel disease and inflammaging
por: Li, Tiemei, et al.
Publicado: (2020)

Cellular Mechanisms of Inflammaging and Periodontal Disease
por: Clark, Daniel, et al.
Publicado: (2022)

Alzheimer’s Disease and Inflammaging
por: Kosyreva, Anna Mikhailovna, et al.
Publicado: (2022)

Microbiomes other than the gut: inflammaging and age-related diseases
por: Santoro, Aurelia, et al.
Publicado: (2020)

Diagnostics of inflammaging in relation to sarcopenia
por: Morawin, Barbara, et al.
Publicado: (2023)

Immunology of Aging: the Birth of Inflammaging
por: Fulop, T., et al.
Publicado: (2021)

Immunosenescence and inflammaging in the aged horse
por: DeNotta, Sally, et al.
Publicado: (2023)

Internalization of the Membrane Attack Complex Triggers NLRP3 Inflammasome Activation and IL-1β Secretion in Human Macrophages
por: Diaz-del-Olmo, Ines, et al.
Publicado: (2021)

Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging
por: Thomas, Rachel, et al.
Publicado: (2020)

lncRNA-Triggered Macrophage Inflammaging Deteriorates Age-Related Diseases
por: Nie, Lulingxiao, et al.
Publicado: (2019)

Immunosenescence, Inflammaging, and Frailty: Role of Myeloid Cells in Age-Related Diseases
por: Bleve, Augusto, et al.
Publicado: (2022)

Understanding how we age: insights into inflammaging
por: Baylis, Daniel, et al.
Publicado: (2013)

Cardiovascular Inflammaging: Mechanisms and Translational Aspects
por: Barcena, Maria Luisa, et al.
Publicado: (2022)

Action Mechanisms of Small Extracellular Vesicles in Inflammaging
por: Mato-Basalo, Rocío, et al.
Publicado: (2022)

Stressor-Induced “Inflammaging” of Vascular Smooth Muscle Cells via Nlrp3-Mediated Pro-inflammatory Auto-Loop
por: Herrmann, Jaqueline, et al.
Publicado: (2021)

Neurovascular Inflammaging in Health and Disease
por: Mészáros, Ádám, et al.
Publicado: (2020)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors
por: Nizami, Sohaib, et al.
Publicado: (2020)

miR-34a: A Promising Target for Inflammaging and Age-Related Diseases
por: Raucci, Angela, et al.
Publicado: (2020)

Adiponectin is associated with inflammaging and age-related salivary gland lipid accumulation
por: Kim, Ji Won, et al.
Publicado: (2023)

Aging without inflammaging: lesson from Spalax
por: Manov, Irena, et al.
Publicado: (2020)

Interconnections between Inflammageing and Immunosenescence during Ageing
por: Teissier, Thibault, et al.
Publicado: (2022)

Hallmarks of Aging in Macrophages: Consequences to Skin Inflammaging
por: Guimarães, Gabriela Rapozo, et al.
Publicado: (2021)

Toll-like receptor 4 activates the NLRP3 inflammasome pathway and periodontal inflammaging by inhibiting Bmi-1 expression
por: Qin, Zi-Yue, et al.
Publicado: (2021)

Canonical and Non-Canonical Activation of NLRP3 Inflammasome at the Crossroad between Immune Tolerance and Intestinal Inflammation
por: Pellegrini, Carolina, et al.
Publicado: (2017)

The Absence of NLRP3-inflammasome Modulates Hepatic Fibrosis Progression, Lipid Metabolism, and Inflammation in KO NLRP3 Mice during Aging
por: Gallego, Paloma, et al.
Publicado: (2020)

Inflammaging as a prodrome to Alzheimer's disease
por: Giunta, Brian, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_6n5ollqrlvc1707hvtv6mke7cj