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Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation

Early diagnosis of colorectal cancer significantly improves survival. However, over half of cases are diagnosed late due to demand exceeding the capacity for colonoscopy - the “gold standard” for screening. Colonoscopy is limited by the outdated design of conventional endoscopes, associated with hig...

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Autores principales: Martin, James W., Scaglioni, Bruno, Norton, Joseph C., Subramanian, Venkataraman, Arezzo, Alberto, Obstein, Keith L., Valdastri, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571595/
https://www.ncbi.nlm.nih.gov/pubmed/33089071
http://dx.doi.org/10.1038/s42256-020-00231-9
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author Martin, James W.
Scaglioni, Bruno
Norton, Joseph C.
Subramanian, Venkataraman
Arezzo, Alberto
Obstein, Keith L.
Valdastri, Pietro
author_facet Martin, James W.
Scaglioni, Bruno
Norton, Joseph C.
Subramanian, Venkataraman
Arezzo, Alberto
Obstein, Keith L.
Valdastri, Pietro
author_sort Martin, James W.
collection PubMed
description Early diagnosis of colorectal cancer significantly improves survival. However, over half of cases are diagnosed late due to demand exceeding the capacity for colonoscopy - the “gold standard” for screening. Colonoscopy is limited by the outdated design of conventional endoscopes, associated with high complexity of use, cost and pain. Magnetic endoscopes represent a promising alternative, overcoming drawbacks of pain and cost, but struggle to reach the translational stage as magnetic manipulation is complex and unintuitive. In this work, we use machine vision to develop intelligent and autonomous control of a magnetic endoscope, for the first time enabling non-expert users to effectively perform magnetic colonoscopy in-vivo. We combine the use of robotics, computer vision and advanced control to offer an intuitive and effective endoscopic system. Moreover, we define the characteristics required to achieve autonomy in robotic endoscopy. The paradigm described here can be adopted in a variety of applications where navigation in unstructured environments is required, such as catheters, pancreatic endoscopy, bronchoscopy, and gastroscopy. This work brings alternative endoscopic technologies closer to the translational stage, increasing availability of early-stage cancer treatments.
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spelling pubmed-75715952021-04-01 Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation Martin, James W. Scaglioni, Bruno Norton, Joseph C. Subramanian, Venkataraman Arezzo, Alberto Obstein, Keith L. Valdastri, Pietro Nat Mach Intell Article Early diagnosis of colorectal cancer significantly improves survival. However, over half of cases are diagnosed late due to demand exceeding the capacity for colonoscopy - the “gold standard” for screening. Colonoscopy is limited by the outdated design of conventional endoscopes, associated with high complexity of use, cost and pain. Magnetic endoscopes represent a promising alternative, overcoming drawbacks of pain and cost, but struggle to reach the translational stage as magnetic manipulation is complex and unintuitive. In this work, we use machine vision to develop intelligent and autonomous control of a magnetic endoscope, for the first time enabling non-expert users to effectively perform magnetic colonoscopy in-vivo. We combine the use of robotics, computer vision and advanced control to offer an intuitive and effective endoscopic system. Moreover, we define the characteristics required to achieve autonomy in robotic endoscopy. The paradigm described here can be adopted in a variety of applications where navigation in unstructured environments is required, such as catheters, pancreatic endoscopy, bronchoscopy, and gastroscopy. This work brings alternative endoscopic technologies closer to the translational stage, increasing availability of early-stage cancer treatments. 2020-10-12 2020-10 /pmc/articles/PMC7571595/ /pubmed/33089071 http://dx.doi.org/10.1038/s42256-020-00231-9 Text en Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Martin, James W.
Scaglioni, Bruno
Norton, Joseph C.
Subramanian, Venkataraman
Arezzo, Alberto
Obstein, Keith L.
Valdastri, Pietro
Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
title Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
title_full Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
title_fullStr Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
title_full_unstemmed Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
title_short Enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
title_sort enabling the future of colonoscopy with intelligent and autonomous magnetic manipulation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571595/
https://www.ncbi.nlm.nih.gov/pubmed/33089071
http://dx.doi.org/10.1038/s42256-020-00231-9
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