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Examination of a first-in-class bis-dialkylnorspermidine-terphenyl antibiotic in topical formulation against mono and polymicrobial biofilms
Biofilm-impaired tissue is a significant factor in chronic wounds such as diabetic foot ulcers. Most, if not all, anti-biotics in clinical use have been optimized against planktonic phenotypes. In this study, an in vitro assessment was performed to determine the potential efficacy of a first-in-clas...
Autores principales: | Miller, Mariël, Rogers, Jeffery C., Badham, Marissa A., Cadenas, Lousili, Brightwell, Eian, Adams, Jacob, Tyler, Cole, Sebahar, Paul R., Haussener, Travis J., Reddy, Hariprasada Reddy Kanna, Looper, Ryan E., Williams, Dustin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571676/ https://www.ncbi.nlm.nih.gov/pubmed/33075071 http://dx.doi.org/10.1371/journal.pone.0234832 |
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