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Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis

OBJECTIVE: This review was done to determine the prevalence of metabolic syndrome (MS) among adult general population in India. We also wanted to find the gender, setting, and region-wide distribution of MS in India. METHODS: We conducted systematic searches in various databases including Medline, S...

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Autores principales: Krishnamoorthy, Yuvaraj, Rajaa, Sathish, Murali, Sharan, Rehman, Tanveer, Sahoo, Jayaprakash, Kar, Sitanshu Sekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571716/
https://www.ncbi.nlm.nih.gov/pubmed/33075086
http://dx.doi.org/10.1371/journal.pone.0240971
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author Krishnamoorthy, Yuvaraj
Rajaa, Sathish
Murali, Sharan
Rehman, Tanveer
Sahoo, Jayaprakash
Kar, Sitanshu Sekhar
author_facet Krishnamoorthy, Yuvaraj
Rajaa, Sathish
Murali, Sharan
Rehman, Tanveer
Sahoo, Jayaprakash
Kar, Sitanshu Sekhar
author_sort Krishnamoorthy, Yuvaraj
collection PubMed
description OBJECTIVE: This review was done to determine the prevalence of metabolic syndrome (MS) among adult general population in India. We also wanted to find the gender, setting, and region-wide distribution of MS in India. METHODS: We conducted systematic searches in various databases including Medline, ScienceDirect, Cochrane library and Google Scholar from inception until August 2019. We included studies conducted in India reporting the prevalence of MS among adults aged 18 years or more. We used the Newcastle Ottawa scale to assess the quality of included studies. We carried out a meta-analysis with random-effects model and reported pooled prevalence with 95% confidence intervals (CIs). We used the Funnel plot to assess publication biases. RESULTS: In total, we analysed 113 data from 111 studies with 133,926 participants. Majority of the included studies (76 out of 111) had low risk of bias. We found significant heterogeneity among the included studies (p<0.001). We also found a symmetrical funnel plot indicating an absence of publication bias. The prevalence of MS among adult population in India was 30% (95%CI: 28%-33%). There was a steady increase in the burden across the age groups from 13% (18–29 years group) to 50% (50–59 years). We also found that people living in urban areas (32%; 95%CI: 29%-36%) had higher prevalence when compared to tribal (28%; 95%CI: 21%-36%) or rural adults (22%; 95%CI: 20%-25%). Gender distribution of MS showed that the females had higher prevalence (35%; 95%CI: 31%-38%) when compared to males 26% (95%CI: 22%-29%). CONCLUSION: Almost one in three adults in India suffer from MS. Females, people living in urban areas and in northeast region had higher prevalence of MS. Development and implementation of policies and protocols for the screening of MS would enable us in early diagnosis and treatment with special focus towards the vulnerable and high-risk groups.
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spelling pubmed-75717162020-10-26 Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis Krishnamoorthy, Yuvaraj Rajaa, Sathish Murali, Sharan Rehman, Tanveer Sahoo, Jayaprakash Kar, Sitanshu Sekhar PLoS One Research Article OBJECTIVE: This review was done to determine the prevalence of metabolic syndrome (MS) among adult general population in India. We also wanted to find the gender, setting, and region-wide distribution of MS in India. METHODS: We conducted systematic searches in various databases including Medline, ScienceDirect, Cochrane library and Google Scholar from inception until August 2019. We included studies conducted in India reporting the prevalence of MS among adults aged 18 years or more. We used the Newcastle Ottawa scale to assess the quality of included studies. We carried out a meta-analysis with random-effects model and reported pooled prevalence with 95% confidence intervals (CIs). We used the Funnel plot to assess publication biases. RESULTS: In total, we analysed 113 data from 111 studies with 133,926 participants. Majority of the included studies (76 out of 111) had low risk of bias. We found significant heterogeneity among the included studies (p<0.001). We also found a symmetrical funnel plot indicating an absence of publication bias. The prevalence of MS among adult population in India was 30% (95%CI: 28%-33%). There was a steady increase in the burden across the age groups from 13% (18–29 years group) to 50% (50–59 years). We also found that people living in urban areas (32%; 95%CI: 29%-36%) had higher prevalence when compared to tribal (28%; 95%CI: 21%-36%) or rural adults (22%; 95%CI: 20%-25%). Gender distribution of MS showed that the females had higher prevalence (35%; 95%CI: 31%-38%) when compared to males 26% (95%CI: 22%-29%). CONCLUSION: Almost one in three adults in India suffer from MS. Females, people living in urban areas and in northeast region had higher prevalence of MS. Development and implementation of policies and protocols for the screening of MS would enable us in early diagnosis and treatment with special focus towards the vulnerable and high-risk groups. Public Library of Science 2020-10-19 /pmc/articles/PMC7571716/ /pubmed/33075086 http://dx.doi.org/10.1371/journal.pone.0240971 Text en © 2020 Krishnamoorthy et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Krishnamoorthy, Yuvaraj
Rajaa, Sathish
Murali, Sharan
Rehman, Tanveer
Sahoo, Jayaprakash
Kar, Sitanshu Sekhar
Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis
title Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis
title_full Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis
title_fullStr Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis
title_full_unstemmed Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis
title_short Prevalence of metabolic syndrome among adult population in India: A systematic review and meta-analysis
title_sort prevalence of metabolic syndrome among adult population in india: a systematic review and meta-analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571716/
https://www.ncbi.nlm.nih.gov/pubmed/33075086
http://dx.doi.org/10.1371/journal.pone.0240971
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