Cargando…

Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis

BACKGROUND: Endometriosis (EMT) is one of the common diseases of women of childbearing age. EMT destroys the anatomical structure of the pelvis, which leads to abnormal ovulation and endocrine abnormalities. It also affects embryo implantation and makes patients infertile. Recently, it is confirmed...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Xiusong, Chen, Jing, Ou, Peiqi, Chen, Jingqin, Lan, Shaohang, Luo, Jiajing, Luo, Yehao, Shang, Yuzhi, Fang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571967/
https://www.ncbi.nlm.nih.gov/pubmed/33080720
http://dx.doi.org/10.1097/MD.0000000000022698
_version_ 1783597252168646656
author Tang, Xiusong
Chen, Jing
Ou, Peiqi
Chen, Jingqin
Lan, Shaohang
Luo, Jiajing
Luo, Yehao
Shang, Yuzhi
Fang, Gang
author_facet Tang, Xiusong
Chen, Jing
Ou, Peiqi
Chen, Jingqin
Lan, Shaohang
Luo, Jiajing
Luo, Yehao
Shang, Yuzhi
Fang, Gang
author_sort Tang, Xiusong
collection PubMed
description BACKGROUND: Endometriosis (EMT) is one of the common diseases of women of childbearing age. EMT destroys the anatomical structure of the pelvis, which leads to abnormal ovulation and endocrine abnormalities. It also affects embryo implantation and makes patients infertile. Recently, it is confirmed that Chinese medicine also have an excellent clinical efficacy on EMT. Compared with the conventional western medicine treatment, it effectively relieve pain and other concomitant symptoms. METHODS AND ANALYSIS: The following databases will be searched for relevant information before July 2020: PubMed, Embase, Cochrane Library, Web of Science, and CNKI. Major results: the overall effective rate, VAS score. Secondary outcomes: blood serum estradiol (E2), progesterone (P), Follicle-Stimulating Hormone (FSH), adverse events. Data will be collected independently by 2 researchers, and the risk of bias in meta-analysis will be evaluated according to “Cochrane Handbook for Systematic Reviews of Interventions”. All data analysis will be conducted using Review Manager V.5.3. and Stata V.12.0. RESULTS: The curative effect and safety of Chinese herbal compound prescription treatment for EMT patients will be evaluated systematically. CONCLUSION: The systematic review of this study will summarize the currently published evidence of Chinese herbal compound prescription treatment for EMT to further guide its promotion and application. ETHICS AND DISSEMINATION: The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OPEN SCIENCE FRAMEWORK (OSF) REGISTRATION NUMBER: https://osf.io/p5nrk.
format Online
Article
Text
id pubmed-7571967
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-75719672020-10-29 Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis Tang, Xiusong Chen, Jing Ou, Peiqi Chen, Jingqin Lan, Shaohang Luo, Jiajing Luo, Yehao Shang, Yuzhi Fang, Gang Medicine (Baltimore) 5600 BACKGROUND: Endometriosis (EMT) is one of the common diseases of women of childbearing age. EMT destroys the anatomical structure of the pelvis, which leads to abnormal ovulation and endocrine abnormalities. It also affects embryo implantation and makes patients infertile. Recently, it is confirmed that Chinese medicine also have an excellent clinical efficacy on EMT. Compared with the conventional western medicine treatment, it effectively relieve pain and other concomitant symptoms. METHODS AND ANALYSIS: The following databases will be searched for relevant information before July 2020: PubMed, Embase, Cochrane Library, Web of Science, and CNKI. Major results: the overall effective rate, VAS score. Secondary outcomes: blood serum estradiol (E2), progesterone (P), Follicle-Stimulating Hormone (FSH), adverse events. Data will be collected independently by 2 researchers, and the risk of bias in meta-analysis will be evaluated according to “Cochrane Handbook for Systematic Reviews of Interventions”. All data analysis will be conducted using Review Manager V.5.3. and Stata V.12.0. RESULTS: The curative effect and safety of Chinese herbal compound prescription treatment for EMT patients will be evaluated systematically. CONCLUSION: The systematic review of this study will summarize the currently published evidence of Chinese herbal compound prescription treatment for EMT to further guide its promotion and application. ETHICS AND DISSEMINATION: The private information from individuals will not be published. This systematic review also will not involve endangering participant rights. Ethical approval is not required. The results may be published in a peer-reviewed journal or disseminated in relevant conferences. OPEN SCIENCE FRAMEWORK (OSF) REGISTRATION NUMBER: https://osf.io/p5nrk. Lippincott Williams & Wilkins 2020-10-16 /pmc/articles/PMC7571967/ /pubmed/33080720 http://dx.doi.org/10.1097/MD.0000000000022698 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 5600
Tang, Xiusong
Chen, Jing
Ou, Peiqi
Chen, Jingqin
Lan, Shaohang
Luo, Jiajing
Luo, Yehao
Shang, Yuzhi
Fang, Gang
Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis
title Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis
title_full Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis
title_fullStr Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis
title_full_unstemmed Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis
title_short Chinese herbal compound prescription for Endometriosis: A protocol for systematic review and meta-analysis
title_sort chinese herbal compound prescription for endometriosis: a protocol for systematic review and meta-analysis
topic 5600
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571967/
https://www.ncbi.nlm.nih.gov/pubmed/33080720
http://dx.doi.org/10.1097/MD.0000000000022698
work_keys_str_mv AT tangxiusong chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT chenjing chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT oupeiqi chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT chenjingqin chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT lanshaohang chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT luojiajing chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT luoyehao chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT shangyuzhi chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis
AT fanggang chineseherbalcompoundprescriptionforendometriosisaprotocolforsystematicreviewandmetaanalysis