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Regulatory role and mechanism of the inhibition of the Mcl-1 pathway during apoptosis and polarization of H37Rv-infected macrophages

BACKGROUND: Myeloid cell leukemia-1 (Mcl-1) plays an important role in the clearance of Mycobacterium tuberculosis (MTB) infection. It has the effect of anti-apoptosis, protecting macrophages that have engulfed pathogens and preventing pathogen clearance. Meanwhile, the MAPK signaling pathway plays...

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Detalles Bibliográficos
Autores principales:	Han, Ling, Lu, Yang, Wang, Xiaofang, Zhang, Shujun, Wang, Yingzi, Wu, Fang, Zhang, Wanjiang, Wang, Xinmin, Zhang, Le
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	4900
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572003/ https://www.ncbi.nlm.nih.gov/pubmed/33080678 http://dx.doi.org/10.1097/MD.0000000000022438

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