Cargando…
Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice
Clinical studies demonstrated that nonalcoholic steatohepatitis is associated with liver-related outcomes in chronic hepatitis B. Furthermore, primary biliary fibrosis and biliary atresia occurred in patients with HBV infection. Interestingly, hepatitis B virus surface protein (HBs) transgenic mice...
Autores principales: | Irungbam, Karuna, Roderfeld, Martin, Glimm, Hannah, Hempel, Felix, Schneider, Franziska, Hehr, Laura, Glebe, Dieter, Churin, Yuri, Morlock, Gertrud, Yüce, Imanuel, Roeb, Elke |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572243/ https://www.ncbi.nlm.nih.gov/pubmed/32612285 http://dx.doi.org/10.1038/s41374-020-0457-9 |
Ejemplares similares
-
Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2
por: Irungbam, Karuna, et al.
Publicado: (2019) -
Pharmacologic Antagonization of Cannabinoid Receptor 1 Improves Cholestasis in Abcb4(-/-) Mice
por: Helmrich, Nora, et al.
Publicado: (2021) -
Genomic Methylation Inhibits Expression of Hepatitis B Virus Envelope Protein in Transgenic Mice: A Non-Infectious Mouse Model to Study Silencing of HBV Surface Antigen Genes
por: Graumann, Franziska, et al.
Publicado: (2015) -
Lipid Storage and Interferon Response Determine the Phenotype of Ground Glass Hepatocytes in Mice and Humans
por: Churin, Yuri, et al.
Publicado: (2021) -
Depletion of Bone Marrow-Derived Fibrocytes Attenuates TAA-Induced Liver Fibrosis in Mice
por: Hempel, Felix, et al.
Publicado: (2019)