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Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia
The objective of this study was to investigate associations between education in early life and cognitive impairment in later life in Colombia. Participants were community-dwelling adults aged 60 years or older from the National Study of Health, Wellbeing and Ageing. Trained interviewers administere...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572407/ https://www.ncbi.nlm.nih.gov/pubmed/33077810 http://dx.doi.org/10.1038/s41598-020-74822-2 |
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author | O’Donovan, Gary Hamer, Mark Sarmiento, Olga L. Hessel, Philipp |
author_facet | O’Donovan, Gary Hamer, Mark Sarmiento, Olga L. Hessel, Philipp |
author_sort | O’Donovan, Gary |
collection | PubMed |
description | The objective of this study was to investigate associations between education in early life and cognitive impairment in later life in Colombia. Participants were community-dwelling adults aged 60 years or older from the National Study of Health, Wellbeing and Ageing. Trained interviewers administered a shorter version of the mini-mental state examination. Cognitive impairment was defined as the lowest tertile in the main analysis and as a score of 12 or less out of 19 in the sensitivity analysis. Logistic regression models were adjusted for education, other early life characteristics, and later life characteristics. The prevalence of cognitive impairment was 17.93% in the main analysis (n = 16,505). Compared with participants with no education, the fully adjusted odds ratio for cognitive impairment was 0.57 (95% confidence interval: 0.52, 0.63) in those with some primary education and 0.29 (95% confidence interval: 0.25, 0.34) in those with some secondary education or more. The population attributable fraction for education suggests that at least 10% of cases of cognitive impairment would be eliminated if all children received an education. Similar results were observed in the sensitivity analysis (n = 20,174). This study suggests that education in early life markedly reduces the probability of cognitive impairment in late life in Colombia. |
format | Online Article Text |
id | pubmed-7572407 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75724072020-10-21 Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia O’Donovan, Gary Hamer, Mark Sarmiento, Olga L. Hessel, Philipp Sci Rep Article The objective of this study was to investigate associations between education in early life and cognitive impairment in later life in Colombia. Participants were community-dwelling adults aged 60 years or older from the National Study of Health, Wellbeing and Ageing. Trained interviewers administered a shorter version of the mini-mental state examination. Cognitive impairment was defined as the lowest tertile in the main analysis and as a score of 12 or less out of 19 in the sensitivity analysis. Logistic regression models were adjusted for education, other early life characteristics, and later life characteristics. The prevalence of cognitive impairment was 17.93% in the main analysis (n = 16,505). Compared with participants with no education, the fully adjusted odds ratio for cognitive impairment was 0.57 (95% confidence interval: 0.52, 0.63) in those with some primary education and 0.29 (95% confidence interval: 0.25, 0.34) in those with some secondary education or more. The population attributable fraction for education suggests that at least 10% of cases of cognitive impairment would be eliminated if all children received an education. Similar results were observed in the sensitivity analysis (n = 20,174). This study suggests that education in early life markedly reduces the probability of cognitive impairment in late life in Colombia. Nature Publishing Group UK 2020-10-19 /pmc/articles/PMC7572407/ /pubmed/33077810 http://dx.doi.org/10.1038/s41598-020-74822-2 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article O’Donovan, Gary Hamer, Mark Sarmiento, Olga L. Hessel, Philipp Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia |
title | Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia |
title_full | Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia |
title_fullStr | Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia |
title_full_unstemmed | Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia |
title_short | Education in early life markedly reduces the probability of cognitive impairment in later life in Colombia |
title_sort | education in early life markedly reduces the probability of cognitive impairment in later life in colombia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572407/ https://www.ncbi.nlm.nih.gov/pubmed/33077810 http://dx.doi.org/10.1038/s41598-020-74822-2 |
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