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Detection of early stage pancreatic cancer using 5-hydroxymethylcytosine signatures in circulating cell free DNA
Pancreatic cancer is often detected late, when curative therapies are no longer possible. Here, we present non-invasive detection of pancreatic ductal adenocarcinoma (PDAC) by 5-hydroxymethylcytosine (5hmC) changes in circulating cell free DNA from a PDAC cohort (n = 64) in comparison with a non-can...
Autores principales: | Guler, Gulfem D., Ning, Yuhong, Ku, Chin-Jen, Phillips, Tierney, McCarthy, Erin, Ellison, Christopher K., Bergamaschi, Anna, Collin, Francois, Lloyd, Paul, Scott, Aaron, Antoine, Michael, Wang, Wendy, Chau, Kim, Ashworth, Alan, Quake, Stephen R., Levy, Samuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572413/ https://www.ncbi.nlm.nih.gov/pubmed/33077732 http://dx.doi.org/10.1038/s41467-020-18965-w |
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