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A streamlined pipeline for multiplexed quantitative site-specific N-glycoproteomics

Regulation of protein N-glycosylation is essential in human cells. However, large-scale, accurate, and site-specific quantification of glycosylation is still technically challenging. We here introduce SugarQuant, an integrated mass spectrometry-based pipeline comprising protein aggregation capture (...

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Detalles Bibliográficos
Autores principales: Fang, Pan, Ji, Yanlong, Silbern, Ivan, Doebele, Carmen, Ninov, Momchil, Lenz, Christof, Oellerich, Thomas, Pan, Kuan-Ting, Urlaub, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572468/
https://www.ncbi.nlm.nih.gov/pubmed/33077710
http://dx.doi.org/10.1038/s41467-020-19052-w

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