Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα–dependent but microbiota-independent tertiary lymphoid tissue formation

Aging has multifaceted effects on the immune system, but how aging affects tissue-specific immunity is not well-defined. Bladder diseases characterized by chronic inflammation are highly prevalent in older women, but mechanisms by which aging promotes these pathologies remain unknown. Tissue transcr...

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Detalles Bibliográficos
Autores principales: Ligon, Marianne M., Wang, Caihong, DeJong, Erica N., Schulz, Christian, Bowdish, Dawn M. E., Mysorekar, Indira U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572484/
https://www.ncbi.nlm.nih.gov/pubmed/32366865
http://dx.doi.org/10.1038/s41385-020-0290-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572484/
https://www.ncbi.nlm.nih.gov/pubmed/32366865
http://dx.doi.org/10.1038/s41385-020-0290-x

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