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The Microbiome and the Gut‐Liver‐Brain Axis for Central Nervous System Clinical Pharmacology: Challenges in Specifying and Integrating In Vitro and In Silico Models

The complexity of integrating microbiota into clinical pharmacology, environmental toxicology, and opioid studies arises from bidirectional and multiscale interactions between humans and their many microbiota, notably those of the gut. Hosts and each microbiota are governed by distinct central dogma...

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Detalles Bibliográficos
Autores principales: Hawkins, Kyle G., Casolaro, Caleb, Brown, Jacquelyn A., Edwards, David A., Wikswo, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572575/
https://www.ncbi.nlm.nih.gov/pubmed/32347548
http://dx.doi.org/10.1002/cpt.1870