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The Microbiome and the Gut‐Liver‐Brain Axis for Central Nervous System Clinical Pharmacology: Challenges in Specifying and Integrating In Vitro and In Silico Models
The complexity of integrating microbiota into clinical pharmacology, environmental toxicology, and opioid studies arises from bidirectional and multiscale interactions between humans and their many microbiota, notably those of the gut. Hosts and each microbiota are governed by distinct central dogma...
Autores principales: | Hawkins, Kyle G., Casolaro, Caleb, Brown, Jacquelyn A., Edwards, David A., Wikswo, John P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572575/ https://www.ncbi.nlm.nih.gov/pubmed/32347548 http://dx.doi.org/10.1002/cpt.1870 |
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