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Monitoring Allosteric Interactions with CXCR4 Using NanoBiT Conjugated Nanobodies

Camelid single-domain antibody fragments (nanobodies) offer the specificity of an antibody in a single 15-kDa immunoglobulin domain. Their small size allows for easy genetic manipulation of the nanobody sequence to incorporate protein tags, facilitating their use as biochemical probes. The nanobody...

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Detalles Bibliográficos
Autores principales:	Soave, Mark, Heukers, Raimond, Kellam, Barrie, Woolard, Jeanette, Smit, Martine J., Briddon, Stephen J., Hill, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573392/ https://www.ncbi.nlm.nih.gov/pubmed/32610042 http://dx.doi.org/10.1016/j.chembiol.2020.06.006

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