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Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a cl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573575/ https://www.ncbi.nlm.nih.gov/pubmed/33077840 http://dx.doi.org/10.1038/s41598-020-74690-w |
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author | O’Neill, Søren Francis Dyhrberg Fidelman, Jonas Morten Haarup, Linne Steinar Lund, Christian Konner, Mikkel Brunsgaard |
author_facet | O’Neill, Søren Francis Dyhrberg Fidelman, Jonas Morten Haarup, Linne Steinar Lund, Christian Konner, Mikkel Brunsgaard |
author_sort | O’Neill, Søren Francis Dyhrberg |
collection | PubMed |
description | The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation suggesting a lumbar disk herniation with concomitant radiculopathy and confirmatory recent MRI were included. Additional imaging by CT was performed as part of the study and these were analyzed with specific attention to endplate junction failures. For ethical reasons, the number of participants was kept to a minimum and a total of 26 patients were included. The prevalence (n = 5) of endplate junction failure was found to be statistically significantly lower than that previously reported. Our findings do not echo those previously reported in an Indian population: Endplate junction failure was indeed observed, but at a significantly lower rate. We discuss potential reasons for the difference in findings with due attention to the weaknesses of the current study. |
format | Online Article Text |
id | pubmed-7573575 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-75735752020-10-21 Low prevalence of end plate junction failure in danish patients with lumbar disc herniation O’Neill, Søren Francis Dyhrberg Fidelman, Jonas Morten Haarup, Linne Steinar Lund, Christian Konner, Mikkel Brunsgaard Sci Rep Article The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation suggesting a lumbar disk herniation with concomitant radiculopathy and confirmatory recent MRI were included. Additional imaging by CT was performed as part of the study and these were analyzed with specific attention to endplate junction failures. For ethical reasons, the number of participants was kept to a minimum and a total of 26 patients were included. The prevalence (n = 5) of endplate junction failure was found to be statistically significantly lower than that previously reported. Our findings do not echo those previously reported in an Indian population: Endplate junction failure was indeed observed, but at a significantly lower rate. We discuss potential reasons for the difference in findings with due attention to the weaknesses of the current study. Nature Publishing Group UK 2020-10-19 /pmc/articles/PMC7573575/ /pubmed/33077840 http://dx.doi.org/10.1038/s41598-020-74690-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article O’Neill, Søren Francis Dyhrberg Fidelman, Jonas Morten Haarup, Linne Steinar Lund, Christian Konner, Mikkel Brunsgaard Low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
title | Low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
title_full | Low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
title_fullStr | Low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
title_full_unstemmed | Low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
title_short | Low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
title_sort | low prevalence of end plate junction failure in danish patients with lumbar disc herniation |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573575/ https://www.ncbi.nlm.nih.gov/pubmed/33077840 http://dx.doi.org/10.1038/s41598-020-74690-w |
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