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Low prevalence of end plate junction failure in danish patients with lumbar disc herniation

The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a cl...

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Autores principales: O’Neill, Søren Francis Dyhrberg, Fidelman, Jonas Morten, Haarup, Linne Steinar, Lund, Christian, Konner, Mikkel Brunsgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573575/
https://www.ncbi.nlm.nih.gov/pubmed/33077840
http://dx.doi.org/10.1038/s41598-020-74690-w
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author O’Neill, Søren Francis Dyhrberg
Fidelman, Jonas Morten
Haarup, Linne Steinar
Lund, Christian
Konner, Mikkel Brunsgaard
author_facet O’Neill, Søren Francis Dyhrberg
Fidelman, Jonas Morten
Haarup, Linne Steinar
Lund, Christian
Konner, Mikkel Brunsgaard
author_sort O’Neill, Søren Francis Dyhrberg
collection PubMed
description The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation suggesting a lumbar disk herniation with concomitant radiculopathy and confirmatory recent MRI were included. Additional imaging by CT was performed as part of the study and these were analyzed with specific attention to endplate junction failures. For ethical reasons, the number of participants was kept to a minimum and a total of 26 patients were included. The prevalence (n = 5) of endplate junction failure was found to be statistically significantly lower than that previously reported. Our findings do not echo those previously reported in an Indian population: Endplate junction failure was indeed observed, but at a significantly lower rate. We discuss potential reasons for the difference in findings with due attention to the weaknesses of the current study.
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spelling pubmed-75735752020-10-21 Low prevalence of end plate junction failure in danish patients with lumbar disc herniation O’Neill, Søren Francis Dyhrberg Fidelman, Jonas Morten Haarup, Linne Steinar Lund, Christian Konner, Mikkel Brunsgaard Sci Rep Article The present study was undertaken to determine the prevalence of endplate junction failure in a smaller cohort of Danish patients with lumbar disk herniation and compare this to the previously published data from India. Consecutive patients seen in a large regional hospital spine-care unit, with a clinical presentation suggesting a lumbar disk herniation with concomitant radiculopathy and confirmatory recent MRI were included. Additional imaging by CT was performed as part of the study and these were analyzed with specific attention to endplate junction failures. For ethical reasons, the number of participants was kept to a minimum and a total of 26 patients were included. The prevalence (n = 5) of endplate junction failure was found to be statistically significantly lower than that previously reported. Our findings do not echo those previously reported in an Indian population: Endplate junction failure was indeed observed, but at a significantly lower rate. We discuss potential reasons for the difference in findings with due attention to the weaknesses of the current study. Nature Publishing Group UK 2020-10-19 /pmc/articles/PMC7573575/ /pubmed/33077840 http://dx.doi.org/10.1038/s41598-020-74690-w Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
O’Neill, Søren Francis Dyhrberg
Fidelman, Jonas Morten
Haarup, Linne Steinar
Lund, Christian
Konner, Mikkel Brunsgaard
Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
title Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
title_full Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
title_fullStr Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
title_full_unstemmed Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
title_short Low prevalence of end plate junction failure in danish patients with lumbar disc herniation
title_sort low prevalence of end plate junction failure in danish patients with lumbar disc herniation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573575/
https://www.ncbi.nlm.nih.gov/pubmed/33077840
http://dx.doi.org/10.1038/s41598-020-74690-w
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