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Finding disease modules for cancer and COVID-19 in gene co-expression networks with the Core&Peel method

Genes are organized in functional modules (or pathways), thus their action and their dysregulation in diseases may be better understood by the identification of the modules most affected by the disease (aka disease modules, or active subnetworks). We describe how an algorithm based on the Core&P...

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Detalles Bibliográficos
Autores principales: Lucchetta, Marta, Pellegrini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573595/
https://www.ncbi.nlm.nih.gov/pubmed/33077837
http://dx.doi.org/10.1038/s41598-020-74705-6

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