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Finding disease modules for cancer and COVID-19 in gene co-expression networks with the Core&Peel method
Genes are organized in functional modules (or pathways), thus their action and their dysregulation in diseases may be better understood by the identification of the modules most affected by the disease (aka disease modules, or active subnetworks). We describe how an algorithm based on the Core&P...
Autores principales: | Lucchetta, Marta, Pellegrini, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573595/ https://www.ncbi.nlm.nih.gov/pubmed/33077837 http://dx.doi.org/10.1038/s41598-020-74705-6 |
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