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COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation

The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of com...

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Detalles Bibliográficos
Autores principales: Hussain, Habiba, Sehring, Matthew, Aulakh, Bhagat Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573660/
https://www.ncbi.nlm.nih.gov/pubmed/33101734
http://dx.doi.org/10.1155/2020/8876932
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author Hussain, Habiba
Sehring, Matthew
Aulakh, Bhagat Singh
author_facet Hussain, Habiba
Sehring, Matthew
Aulakh, Bhagat Singh
author_sort Hussain, Habiba
collection PubMed
description The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay.
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spelling pubmed-75736602020-10-22 COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation Hussain, Habiba Sehring, Matthew Aulakh, Bhagat Singh Case Rep Crit Care Case Report The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay. Hindawi 2020-10-17 /pmc/articles/PMC7573660/ /pubmed/33101734 http://dx.doi.org/10.1155/2020/8876932 Text en Copyright © 2020 Habiba Hussain et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Hussain, Habiba
Sehring, Matthew
Aulakh, Bhagat Singh
COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
title COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
title_full COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
title_fullStr COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
title_full_unstemmed COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
title_short COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
title_sort covid-19-associated coagulopathy: a case report of thrombosis despite therapeutic anticoagulation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573660/
https://www.ncbi.nlm.nih.gov/pubmed/33101734
http://dx.doi.org/10.1155/2020/8876932
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