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COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of com...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573660/ https://www.ncbi.nlm.nih.gov/pubmed/33101734 http://dx.doi.org/10.1155/2020/8876932 |
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author | Hussain, Habiba Sehring, Matthew Aulakh, Bhagat Singh |
author_facet | Hussain, Habiba Sehring, Matthew Aulakh, Bhagat Singh |
author_sort | Hussain, Habiba |
collection | PubMed |
description | The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay. |
format | Online Article Text |
id | pubmed-7573660 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-75736602020-10-22 COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation Hussain, Habiba Sehring, Matthew Aulakh, Bhagat Singh Case Rep Crit Care Case Report The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay. Hindawi 2020-10-17 /pmc/articles/PMC7573660/ /pubmed/33101734 http://dx.doi.org/10.1155/2020/8876932 Text en Copyright © 2020 Habiba Hussain et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Hussain, Habiba Sehring, Matthew Aulakh, Bhagat Singh COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation |
title | COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation |
title_full | COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation |
title_fullStr | COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation |
title_full_unstemmed | COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation |
title_short | COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation |
title_sort | covid-19-associated coagulopathy: a case report of thrombosis despite therapeutic anticoagulation |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573660/ https://www.ncbi.nlm.nih.gov/pubmed/33101734 http://dx.doi.org/10.1155/2020/8876932 |
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