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Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China

The COVID-19 pandemic has resulted in increasing number of infections and deaths every day. Lack of specialized treatments for the disease demands preventive measures based on statistical/mathematical models. The analysis of epidemiological curve fitting, on number of daily infections across affecte...

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Autores principales: Attanayake, A. M. C. H., Perera, S. S. N., Jayasinghe, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573661/
https://www.ncbi.nlm.nih.gov/pubmed/33101454
http://dx.doi.org/10.1155/2020/6397063
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author Attanayake, A. M. C. H.
Perera, S. S. N.
Jayasinghe, S.
author_facet Attanayake, A. M. C. H.
Perera, S. S. N.
Jayasinghe, S.
author_sort Attanayake, A. M. C. H.
collection PubMed
description The COVID-19 pandemic has resulted in increasing number of infections and deaths every day. Lack of specialized treatments for the disease demands preventive measures based on statistical/mathematical models. The analysis of epidemiological curve fitting, on number of daily infections across affected countries, provides useful insights on the characteristics of the epidemic. A variety of phenomenological models are available to capture the dynamics of disease spread and growth. The number of daily new infections and cumulative number of infections in COVID-19 over four selected countries, namely, Sri Lanka, Italy, the United States, and Hebei province of China, from the first day of appearance of cases to 2(nd) July 2020 were used in the study. Gompertz, logistic, Weibull, and exponential growth curves were fitted on the cumulative number of infections across countries. AIC, BIC, RMSE, and R(2) were used to determine the best fitting curve for each country. Results revealed that the most appropriate growth curves for Sri Lanka, Italy, the United States, and China (Hebei) are the logistic, Gompertz, Weibull, and Gompertz curves, respectively. Country-wise, overall growth rate, final epidemic size, and short-term forecasts were evaluated using the selected model. Daily log incidences in each country were regressed before and after the identified peak time of the respective outbreak of epidemic. Hence, doubling time/halving time together with daily growth rates and predictions was estimated. Findings and relevant interpretations demonstrate that the outbreak seems to be extinct in Hebei, China, whereas further transmissions are possible in the United States. In Italy and Sri Lanka, current outbreaks transmit in a decreasing rate.
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spelling pubmed-75736612020-10-22 Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China Attanayake, A. M. C. H. Perera, S. S. N. Jayasinghe, S. Comput Math Methods Med Research Article The COVID-19 pandemic has resulted in increasing number of infections and deaths every day. Lack of specialized treatments for the disease demands preventive measures based on statistical/mathematical models. The analysis of epidemiological curve fitting, on number of daily infections across affected countries, provides useful insights on the characteristics of the epidemic. A variety of phenomenological models are available to capture the dynamics of disease spread and growth. The number of daily new infections and cumulative number of infections in COVID-19 over four selected countries, namely, Sri Lanka, Italy, the United States, and Hebei province of China, from the first day of appearance of cases to 2(nd) July 2020 were used in the study. Gompertz, logistic, Weibull, and exponential growth curves were fitted on the cumulative number of infections across countries. AIC, BIC, RMSE, and R(2) were used to determine the best fitting curve for each country. Results revealed that the most appropriate growth curves for Sri Lanka, Italy, the United States, and China (Hebei) are the logistic, Gompertz, Weibull, and Gompertz curves, respectively. Country-wise, overall growth rate, final epidemic size, and short-term forecasts were evaluated using the selected model. Daily log incidences in each country were regressed before and after the identified peak time of the respective outbreak of epidemic. Hence, doubling time/halving time together with daily growth rates and predictions was estimated. Findings and relevant interpretations demonstrate that the outbreak seems to be extinct in Hebei, China, whereas further transmissions are possible in the United States. In Italy and Sri Lanka, current outbreaks transmit in a decreasing rate. Hindawi 2020-10-18 /pmc/articles/PMC7573661/ /pubmed/33101454 http://dx.doi.org/10.1155/2020/6397063 Text en Copyright © 2020 A. M. C. H. Attanayake et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Attanayake, A. M. C. H.
Perera, S. S. N.
Jayasinghe, S.
Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China
title Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China
title_full Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China
title_fullStr Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China
title_full_unstemmed Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China
title_short Phenomenological Modelling of COVID-19 Epidemics in Sri Lanka, Italy, the United States, and Hebei Province of China
title_sort phenomenological modelling of covid-19 epidemics in sri lanka, italy, the united states, and hebei province of china
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573661/
https://www.ncbi.nlm.nih.gov/pubmed/33101454
http://dx.doi.org/10.1155/2020/6397063
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