Cargando…

Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapy: A Review for the Otolaryngologist

BACKGROUND: Cystic fibrosis (CF) is a genetic disease that may result in multiple systemic disorders and potentially fatal severe respiratory compromise. However, the advent of CF transmembrane conductance regulator (CFTR) modulators has changed the management of CF for patients with select mutation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Saangyoung E., Farzal, Zainab, Daniels, M.Leigh Anne, Thorp, Brian D., Zanation, Adam M., Senior, Brent A., Ebert, Charles S., Kimple, Adam J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2020
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573678/ https://www.ncbi.nlm.nih.gov/pubmed/32168995 http://dx.doi.org/10.1177/1945892420912368

Ejemplares similares

Availability of Readable Online Spanish Rhinosinusitis Outcome Measures
por: Lee, Saangyoung E., et al.
Publicado: (2022)

The impact of total immunoglobulin E levels on outcomes of maximal medical therapy for chronic rhinosinusitis
por: Lemos-Rodriguez, Ana M., et al.
Publicado: (2017)

Extramedullary Hematopoiesis in the Sinonasal Cavity: A Case Report and Review of the Literature
por: Clark, Carly A., et al.
Publicado: (2020)

Sinonasal complications of severe acute respiratory syndrome coronavirus‐2: A single center case series
por: Lee, Saangyoung E., et al.
Publicado: (2023)

Sinus Development and Pneumatization in a Primary Ciliary Dyskinesia Cohort
por: Pappa, Andrew K., et al.
Publicado: (2020)

Targeted Activation of Cystic Fibrosis Transmembrane Conductance Regulator
por: Villamizar, Olga, et al.
Publicado: (2019)

Nasopharyngeal Hyalinizing Clear Cell Carcinoma: A Case Report and Review of the Literature
por: Malfitano, Madison J., et al.
Publicado: (2019)

Sinonasal epithelial-myoepithelial carcinoma: Report of a novel subsite and review of the literature
por: Schuman, Theodore A., et al.
Publicado: (2018)

Numerical evaluation of spray position for improved nasal drug delivery
por: Basu, Saikat, et al.
Publicado: (2020)

Glycosylation and the cystic fibrosis transmembrane conductance regulator
por: Scanlin, Thomas F, et al.
Publicado: (2001)

Where Is the Cystic Fibrosis Transmembrane Conductance Regulator?
por: Barbry, Pascal, et al.
Publicado: (2021)

Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives
por: Schmidt, Béla Z, et al.
Publicado: (2016)

The Extrapulmonary Effects of Cystic Fibrosis Transmembrane Conductance Regulator Modulators in Cystic Fibrosis
por: Sergeev, Valentine, et al.
Publicado: (2020)

Acquired cystic fibrosis transmembrane conductance regulator dysfunction
por: Banks, Catherine, et al.
Publicado: (2018)

Cystic fibrosis transmembrane conductance regulator mutations at a referral center for cystic fibrosis
por: Coutinho, Cyntia Arivabeni de Araújo Correia, et al.
Publicado: (2013)

666 Ivacaftor boosts cystic fibrosis transmembrane conductance regulator–mediated nasal potential difference in cystic fibrosis transmembrane conductance regulator knockout mice treated with human cystic fibrosis transmembrane conductance regulator messenger ribonucleic acid lipid nanoparticle
por: Mukherjee, A., et al.
Publicado: (2022)

Alignment of transmembrane regions in the cystic fibrosis transmembrane conductance regulator chloride channel pore
por: Wang, Wuyang, et al.
Publicado: (2011)

The cystic fibrosis transmembrane conductance regulator is an extracellular chloride sensor
por: Broadbent, Steven D., et al.
Publicado: (2014)

The cystic fibrosis transmembrane conductance regulator (CFTR) and its stability
por: Meng, Xin, et al.
Publicado: (2016)

A transistor model for the cystic fibrosis transmembrane conductance regulator
por: Hunt, William D., et al.
Publicado: (2023)

Anti-Inflammatory Influences of Cystic Fibrosis Transmembrane Conductance Regulator Drugs on Lung Inflammation in Cystic Fibrosis
por: Harwood, Kiera H., et al.
Publicado: (2021)

Cystic Fibrosis Transmembrane Conductance Regulator Folding Mutations Reveal Differences in Corrector Efficacy Linked to Increases in Immature Cystic Fibrosis Transmembrane Conductance Regulator Expression
por: Peters, Kathryn W., et al.
Publicado: (2021)

Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator
por: Bartoszewski, Rafal, et al.
Publicado: (2016)

The effect of cystic fibrosis transmembrane conductance regulator modulators on impaired glucose tolerance and cystic fibrosis related diabetes
por: Hasan, Sana, et al.
Publicado: (2022)

Cystic Fibrosis Transmembrane Conductance Regulator Genotype, Not Circulating Catecholamines, Influences Cardiovascular Function in Patients with Cystic Fibrosis
por: Bisch, Alexander L, et al.
Publicado: (2019)

Abnormal localization of cystic fibrosis transmembrane conductance regulator in primary cultures of cystic fibrosis airway epithelia
Publicado: (1992)

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitylation as a Novel Pharmaceutical Target for Cystic Fibrosis
por: Fukuda, Ryosuke, et al.
Publicado: (2020)

A Developmental Role of the Cystic Fibrosis Transmembrane Conductance Regulator in Cystic Fibrosis Lung Disease Pathogenesis
por: Huang, Elena N., et al.
Publicado: (2021)

A New Era for Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Modulator Trials in Infants
por: Wainwright, Claire E.
Publicado: (2022)

Lung Inflammatory Genes in Cystic Fibrosis and Their Relevance to Cystic Fibrosis Transmembrane Conductance Regulator Modulator Therapies
por: Carbone, Annalucia, et al.
Publicado: (2023)

Transmembrane Helices 7 and 8 Confer Aggregation Sensitivity to the Cystic Fibrosis Transmembrane Conductance Regulator
por: Kleizen, Bertrand, et al.
Publicado: (2023)

Corneal Refractive Surgery Considerations in Patients with Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator-Related Disorders
por: Moshirfar, Majid, et al.
Publicado: (2022)

Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator
por: Laselva, Onofrio, et al.
Publicado: (2021)

Cystic fibrosis transmembrane conductance regulator function in patients with chronic pancreatitis
por: Schlosser, Tobias, et al.
Publicado: (2022)

A Proteomic Survey of the Cystic Fibrosis Transmembrane Conductance Regulator Surfaceome
por: Iazzi, Melissa, et al.
Publicado: (2023)

The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator
por: Chen, Eva Y, et al.
Publicado: (2002)

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs
por: Meyerholz, David K., et al.
Publicado: (2018)

Cystic fibrosis transmembrane conductance regulator (CFTR) modulators have differential effects on cystic fibrosis macrophage function
por: Zhang, Shuzhong, et al.
Publicado: (2018)

Reappraisal of Frequency of Common Cystic Fibrosis Transmembrane Conductance Regulator Gene Mutations in Iranian Cystic Fibrosis Patients
por: Khalilzadeh, Soheila, et al.
Publicado: (2018)

Cystic fibrosis patients on cystic fibrosis transmembrane conductance regulator modulators have a reduced incidence of cirrhosis
por: Ramsey, Mitchell L, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ttgdo8kmlu2jbgl9piqouk5n17