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A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams

Optical resolution of far-field optical microscopy is limited by the diffraction of light, while diverse light-matter interactions are used to push the limit. The image resolution limit depends on the type of optical microscopy; however, the current theoretical frameworks provide oversimplified pict...

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Autor principal: Fukutake, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573692/
https://www.ncbi.nlm.nih.gov/pubmed/33077745
http://dx.doi.org/10.1038/s41598-020-73584-1
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author Fukutake, Naoki
author_facet Fukutake, Naoki
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description Optical resolution of far-field optical microscopy is limited by the diffraction of light, while diverse light-matter interactions are used to push the limit. The image resolution limit depends on the type of optical microscopy; however, the current theoretical frameworks provide oversimplified pictures of image formation and resolution that only address individual types of microscopy and light-matter interactions. To compare the fundamental optical resolutions of all types of microscopy and to codify a unified image-formation theory, a new method that describes the influence of light-matter interactions on the resolution limit is required. Here, we develop an intuitive technique using double-sided Feynman diagrams that depict light-matter interactions to provide a bird’s-eye view of microscopy classification. This diagrammatic methodology also allows for the optical resolution calculation of all types of microscopy. We show a guidepost for understanding the potential resolution and limitation of all optical microscopy. This principle opens the door to study unexplored theoretical questions and lead to new applications.
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spelling pubmed-75736922020-10-21 A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams Fukutake, Naoki Sci Rep Article Optical resolution of far-field optical microscopy is limited by the diffraction of light, while diverse light-matter interactions are used to push the limit. The image resolution limit depends on the type of optical microscopy; however, the current theoretical frameworks provide oversimplified pictures of image formation and resolution that only address individual types of microscopy and light-matter interactions. To compare the fundamental optical resolutions of all types of microscopy and to codify a unified image-formation theory, a new method that describes the influence of light-matter interactions on the resolution limit is required. Here, we develop an intuitive technique using double-sided Feynman diagrams that depict light-matter interactions to provide a bird’s-eye view of microscopy classification. This diagrammatic methodology also allows for the optical resolution calculation of all types of microscopy. We show a guidepost for understanding the potential resolution and limitation of all optical microscopy. This principle opens the door to study unexplored theoretical questions and lead to new applications. Nature Publishing Group UK 2020-10-19 /pmc/articles/PMC7573692/ /pubmed/33077745 http://dx.doi.org/10.1038/s41598-020-73584-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Fukutake, Naoki
A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams
title A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams
title_full A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams
title_fullStr A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams
title_full_unstemmed A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams
title_short A general theory of far-field optical microscopy image formation and resolution limit using double-sided Feynman diagrams
title_sort general theory of far-field optical microscopy image formation and resolution limit using double-sided feynman diagrams
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573692/
https://www.ncbi.nlm.nih.gov/pubmed/33077745
http://dx.doi.org/10.1038/s41598-020-73584-1
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