Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report

Tubulocystic renal cell carcinoma (RCC) is one of the newly recognized subtypes of RCC. It has a unique cystic morphology and indolent behavior. During the last decade, few studies have been published describing tubulocystic RCC with poorly differentiated foci. A subset of these cases are associated...

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Autores principales: Al-Hussain, Turki O., Alahmadi, Bushra, Junejo, Noor Nabi, Alshammari, Kawther, Bakshi, Nasir, Alzahrani, Hassan Messfer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573761/
https://www.ncbi.nlm.nih.gov/pubmed/33101988
http://dx.doi.org/10.1016/j.eucr.2020.101236
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author Al-Hussain, Turki O.
Alahmadi, Bushra
Junejo, Noor Nabi
Alshammari, Kawther
Bakshi, Nasir
Alzahrani, Hassan Messfer
author_facet Al-Hussain, Turki O.
Alahmadi, Bushra
Junejo, Noor Nabi
Alshammari, Kawther
Bakshi, Nasir
Alzahrani, Hassan Messfer
author_sort Al-Hussain, Turki O.
collection PubMed
description Tubulocystic renal cell carcinoma (RCC) is one of the newly recognized subtypes of RCC. It has a unique cystic morphology and indolent behavior. During the last decade, few studies have been published describing tubulocystic RCC with poorly differentiated foci. A subset of these cases are associated with loss of fumarate hydratase which is a characteristic feature of hereditary leiomyomatosis and renal cell carcinoma-associated RCC. However, these two entities represent two distinct subtypes of RCC in the recent WHO Classification of kidney tumors. Herein, we are describing a rare case of tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase.
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spelling pubmed-75737612020-10-23 Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report Al-Hussain, Turki O. Alahmadi, Bushra Junejo, Noor Nabi Alshammari, Kawther Bakshi, Nasir Alzahrani, Hassan Messfer Urol Case Rep Oncology Tubulocystic renal cell carcinoma (RCC) is one of the newly recognized subtypes of RCC. It has a unique cystic morphology and indolent behavior. During the last decade, few studies have been published describing tubulocystic RCC with poorly differentiated foci. A subset of these cases are associated with loss of fumarate hydratase which is a characteristic feature of hereditary leiomyomatosis and renal cell carcinoma-associated RCC. However, these two entities represent two distinct subtypes of RCC in the recent WHO Classification of kidney tumors. Herein, we are describing a rare case of tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase. Elsevier 2020-05-28 /pmc/articles/PMC7573761/ /pubmed/33101988 http://dx.doi.org/10.1016/j.eucr.2020.101236 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Al-Hussain, Turki O.
Alahmadi, Bushra
Junejo, Noor Nabi
Alshammari, Kawther
Bakshi, Nasir
Alzahrani, Hassan Messfer
Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report
title Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report
title_full Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report
title_fullStr Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report
title_full_unstemmed Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report
title_short Tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: A case report
title_sort tubulocystic renal cell carcinoma with poorly differentiated foci and loss of fumarate hydratase: a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573761/
https://www.ncbi.nlm.nih.gov/pubmed/33101988
http://dx.doi.org/10.1016/j.eucr.2020.101236
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