Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report

Localized treatment has recently become an option for treating oligometastatic prostate cancer. Metastasis-directed therapy (MDT) is a new approach for localized treatment, and many clinical trials are ongoing. In the present case, biochemical recurrence occurred 8 months after a radical prostatecto...

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Detalles Bibliográficos
Autores principales: Okuda, Satoshi, Tabata, Ken-ichi, Shimura, Soichiro, Harano, Takahiro, Shiba, Izuru, Iwamura, Masatsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573857/
https://www.ncbi.nlm.nih.gov/pubmed/33102017
http://dx.doi.org/10.1016/j.eucr.2020.101315
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author Okuda, Satoshi
Tabata, Ken-ichi
Shimura, Soichiro
Harano, Takahiro
Shiba, Izuru
Iwamura, Masatsugu
author_facet Okuda, Satoshi
Tabata, Ken-ichi
Shimura, Soichiro
Harano, Takahiro
Shiba, Izuru
Iwamura, Masatsugu
author_sort Okuda, Satoshi
collection PubMed
description Localized treatment has recently become an option for treating oligometastatic prostate cancer. Metastasis-directed therapy (MDT) is a new approach for localized treatment, and many clinical trials are ongoing. In the present case, biochemical recurrence occurred 8 months after a radical prostatectomy for localized prostate cancer, and oligometastases were diagnosed via whole-body magnetic resonance imaging. Metastasis-directed radiotherapy (MDRT) was performed on all oligometastatic sites. After MDRT without androgen deprivation therapy, the prostate-specific antigen (PSA) decreased to an undetectable level and did not increase for 24 months.
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spelling pubmed-75738572020-10-23 Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report Okuda, Satoshi Tabata, Ken-ichi Shimura, Soichiro Harano, Takahiro Shiba, Izuru Iwamura, Masatsugu Urol Case Rep Oncology Localized treatment has recently become an option for treating oligometastatic prostate cancer. Metastasis-directed therapy (MDT) is a new approach for localized treatment, and many clinical trials are ongoing. In the present case, biochemical recurrence occurred 8 months after a radical prostatectomy for localized prostate cancer, and oligometastases were diagnosed via whole-body magnetic resonance imaging. Metastasis-directed radiotherapy (MDRT) was performed on all oligometastatic sites. After MDRT without androgen deprivation therapy, the prostate-specific antigen (PSA) decreased to an undetectable level and did not increase for 24 months. Elsevier 2020-06-23 /pmc/articles/PMC7573857/ /pubmed/33102017 http://dx.doi.org/10.1016/j.eucr.2020.101315 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology
Okuda, Satoshi
Tabata, Ken-ichi
Shimura, Soichiro
Harano, Takahiro
Shiba, Izuru
Iwamura, Masatsugu
Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report
title Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report
title_full Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report
title_fullStr Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report
title_full_unstemmed Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report
title_short Complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: A case report
title_sort complete biochemical response following metastasis-directed radiotherapy for oligometastatic prostate cancer: a case report
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573857/
https://www.ncbi.nlm.nih.gov/pubmed/33102017
http://dx.doi.org/10.1016/j.eucr.2020.101315
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