Phimosis: A rare complication of immunotherapy with durvalumab

We present a case of a 69 year old man with phimosis associated with immunotherapy with durvalumab for metastatic non-small-cell lung cancer. The patient developed vitiligo like dermatosis after the induction dose of durvalumab, subsequent administration of the immunotherapy the patient developed a...

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Detalles Bibliográficos
Autores principales: Vázquez-Lavista, Luis Gabriel, Llorente, Luis, Alatorre-Alexander, Jorge, Ramírez-Muciño, José Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573967/
https://www.ncbi.nlm.nih.gov/pubmed/33102050
http://dx.doi.org/10.1016/j.eucr.2020.101350
Descripción
Sumario:We present a case of a 69 year old man with phimosis associated with immunotherapy with durvalumab for metastatic non-small-cell lung cancer. The patient developed vitiligo like dermatosis after the induction dose of durvalumab, subsequent administration of the immunotherapy the patient developed a fibrous ring of the foreskin. Immune-mediated adverse reactions have been described after the use of durvalumab, but, to our knowledge, there are no reports of phimosis and vitiligo like reactions.

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